Article:

Outcome of primary percutaneous coronary intervention versus thrombolysis in ST segment elevation myocardial infarction in tertiary Centre

Abstract Introduction: As myocardial infarction has become leading cause of death throughout the world, reperfusion therapy either by fibrinolysis or with primary percutaneous coronary intervention (PCI) in appropriate patients becomes necessary. The study aims to evaluate the outcome of patients with ST segment elevation myocardial infarction treated with PCI and fibrinolysis in our setting. Methods: Retrospective analysis for risk factors, complication and in-hospital mortality was done in patients presented with acute ST segment elevation myocardial infarction to emergency department of Manmohan cardiothoracic vascular and transplant centre from April 2012 to April 2013. Results: Total 36 patients were admitted in the study period with ST elevation myocardial infarction and candidate for reperfusion. Half of them had undergone primary PCI. Patients on PCI group were having more Anteroseptal wall involvement, diabetes mellitus, higher Killip class at admission and few patients presented later than 24 hours than in fibrinolysis group. The overall complication rate and in-hospital mortality were similar in both groups (P= 0.062, 0.572 respectively). Conclusion: This study showed similar mortality and complication rate in primary PCI group and Fibrinolytics group in spite the fact that patients in the PCI group had higher baseline risk. Keywords: fibrinolysis, PCI, myocardial infraction