Publication: Hereditary Spherocytosis with Splenomegaly and Cholelithiasis in a Young Male of Western Region of Nepal - A Case Report
Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Hereditary spherocytosis is an autosomal dominant congenital hemolytic anemia
due to defect in RBC membrane protein that commonly presents with intermittent
jaundice, anemia, abdominal pain, splenomegaly and sometimes cholelithiasis.
Due to the membrane defect, there is increased fragility, hemolytic anemia,
marked splenomegaly and hyperbilirubinemia. This is a report of an 11 years old
male diagnosed case of hereditary spherocytosis who presented with jaundice,
splenomegaly and cholelithiasis. He underwent elective open splenectomy and
cholecystectomy after prophylactic immunization for capsulated organisms and
was advised lifelong oral penicillin prophylaxis post-splenectomy.
KEY WORDS
Cholelithiasis, hemolytic anemia, prophylaxis, splenectomy, splenomegaly
Description
Ghimire P, Gurung NV, Shrestha S, Gurung A, Poudel SR, Chapagain A
Department of Surgery
Western Regional Hospital
Pokhara, Nepal
Keywords
Cholelithiasis, Hemolytic anemia, Prophylaxis, Splenectomy, Splenomegaly