Publication:
Study of Histomorphological Patterns of Uterine Leiomyomas: An Observational Study

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorTiwari, Archana
dc.contributor.authorSapkota, Pratima
dc.date.accessioned2025-07-29T06:19:39Z
dc.date.available2025-07-29T06:19:39Z
dc.date.issued2025
dc.descriptionArchana Tiwari Department of Pathology, Lumbini Medical College, Tansen, Palpa, Nepal Pratima Sapkota Department of Pathology, Lumbini Medical College, Tansen, Palpa, Nepal
dc.description.abstractAbstract Introduction: Uterine leiomyoma, also known as a fibroid, is a benign mesenchymal tumor derived from the smooth muscle of the uterus. It is the most common tumor in women with an estimated incidence of 20%-40% in women during their reproductive years. Leiomyoma can occur in any organ, but the most common forms appear in the uterus. This study is conducted to analyze histomorphological patterns of uterine leiomyomas. Methods: An observational cross-section was conducted between 1st June 2021 and 31st May 2023 in the Department of Pathology of a Medical College and Teaching Hospital. Patients with leiomyoma were included in the study. Clinical, sonographic, gross, and histopathology findings were analyzed. Ethical approval for the study was obtained from Institutional Review Committee (Reference Number: LMC10/B-021). Results: There were 100 patients with leiomyoma during the study period, among whom 55 (55%) were 40-49 years old. There were 65 (65%) patients in the group with a parity of two to three. Abnormal uterine bleeding was observed in 60 (60%) of the cases. Histologically 84 (84%) of the cases were simple conventional leiomyoma. The co-existing conditions found were cystic ovarian disease 37 (37%), adenomyosis 19 (19%), and cervical intraepithelial neoplasia 12 (12%). Conclusions: Conventional leiomyoma is the commonest histological subtype and and the most common clinical presentation is abnormal uterine bleeding.
dc.identifierhttps://doi.org/10.31729/jnma.8883
dc.identifier.urihttps://hdl.handle.net/20.500.14572/881
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.titleStudy of Histomorphological Patterns of Uterine Leiomyomas: An Observational Study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage92
oaire.citation.startPage88
relation.isJournalIssueOfPublication533a090f-c8fd-450b-b4ae-5d38d9ad0b45
relation.isJournalIssueOfPublication.latestForDiscovery533a090f-c8fd-450b-b4ae-5d38d9ad0b45
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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