Article:
Prevalence of Hemolysis, Elevated Liver Enzymes, Low Platelet Count Syndrome in Pregnant Women in a Tertiary Care Hospital

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorSitaula, Sarita
dc.contributor.authorManandhar, Tara
dc.contributor.authorThapa, Baburam Dixit
dc.contributor.authorShrestha, Ramesh
dc.contributor.authorDharel, Dinesh
dc.date.accessioned2026-08-11T05:14:59Z
dc.date.available2026-08-11T05:14:59Z
dc.date.issued2020
dc.descriptionSarita Sitaula Department of Obstetrics and Gynecology, BP Koirala Institute of Health Sciences, Dharan, Nepal Tara Manandhar Department of Obstetrics and Gynecology, BP Koirala Institute of Health Sciences, Dharan, Nepal Baburam Dixit Thapa Department of Obstetrics and Gynecology, BP Koirala Institute of Health Sciences, Dharan, Nepal Ramesh Shrestha Department of Obstetrics and Gynecology, BP Koirala Institute of Health Sciences, Dharan, Nepal Dinesh Dharel Department of Pediatrics and Department of Community Health and Epidemiology, University of Saskatchewan, Canada
dc.description.abstractAbstract Introduction: Hemolysis, Elevated Liver Enzymes, Low Platelet count syndrome refers to biological syndrome occurring in pre-eclamptic and eclamptic women. There is a higher rate of maternal and perinatal morbidity and mortality due to the syndrome. So, the objective of the study is to find the prevalence and maternal- perinatal outcome in the syndrome. Methods: A descriptive cross-sectional study was done in a tertiary care hospital from 1st April 2017 to 30th March 2018 after obtaining ethical clearance from the Institutional Review Committee. The inclusion criteria were patients giving consent for participation and those who delivered in our hospital. Patient with the syndrome who delivered outside and referred in the postpartum period was excluded because details of the neonate may not be available. The Statistical Package for Social Sciences version 21 was used for the analysis of the data. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Out of 11974 deliveries, the prevalence of Hemolysis, Elevated Liver Enzymes, Low Platelet count syndrome was 83 (0.69%) at 95% Confidence Interval (59.06-78.94). Maternal complications were seen in 19 (22.9%) and common complications being acute renal failure 9 (47.37%) followed by postpartum hemorrhage 4 (21.05%). Nearly 27 (33%) of patients required maternal ICU stay and there was one maternal mortality. Conclusions: Hemolysis, Elevated Liver Enzymes, Low Platelet count syndrome is one of the major causes of maternal and perinatal morbidity and mortality. Hence early recognition and prompt management may improve maternal and fetal outcomes. Keywords: cesarean section, HELLP syndrome, maternal mortality
dc.identifierhttps://doi.org/10.31729/jnma.4921
dc.identifier.urihttps://hdl.handle.net/20.500.14572/7196
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectcesarean section
dc.subjectHELLP syndrome
dc.subjectmaternal mortality
dc.titlePrevalence of Hemolysis, Elevated Liver Enzymes, Low Platelet Count Syndrome in Pregnant Women in a Tertiary Care Hospital
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage408
oaire.citation.startPage405
relation.isJournalIssueOfPublication68e7987e-f8d8-4254-97f6-36ef07649cc0
relation.isJournalIssueOfPublication.latestForDiscovery68e7987e-f8d8-4254-97f6-36ef07649cc0
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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