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Birth Weight Pattern and Immediate Morbidities in 452 Neonates Born to Diabetic Mothers: A Tertiary Centre Perspective

creativeworkseries.issnISSN 1990-7974 eISSN 1990-7982
dc.contributor.authorBhat. Y, Ramesh
dc.contributor.authorReddy, Narasimha
dc.contributor.authorLewis, Leslie
dc.date.accessioned2025-10-16T09:25:56Z
dc.date.available2025-10-16T09:25:56Z
dc.date.issued2023
dc.descriptionRamesh Bhat. Y Professor and Unit Department of Paediatrics, Kasturba Medical College, Manipal Academy of Higher Education (MAHE) University, Manipal, Karnataka 576104, India Narasimha Reddy HeadDepartment of Paediatrics, Kasturba Medical College, Manipal Academy of Higher Education (MAHE) University, Manipal, Karnataka 576104, India https://orcid.org/0000-0002-3233-3980 Leslie Lewis Resident Department of Paediatrics, Kasturba Medical College, manipal Manipal Academy of Higher Education (MAHE) University, Manipal, India- 576104 https://orcid.org/0000-0002-3467-6821
dc.description.abstractAbstract: Introduction: Neonates born to diabetic mothers continue to remain as highrisk neonates despite advanced care of gestational diabetes mellitus (GDM). Morbidities including macrosomia remain a significant problem. We aimed to study the birth weight pattern, incidence of hypoglycemia and immediate morbidities in neonates born to diabetic mothers. Methods: Neonates born to diabetic mothers were prospectively studied over 18 months. The birth weight pattern, hypoglycemia, biochemical abnormalities, hyperbilirubinemia and other systemic morbidities were studied. Results: Among 4654 live births, 516 (11%) neonates were born to diabetic mothers. After excluding 64, 452 neonates were further studied. Overall, 76.1% had normal birth weight. Large for gestational age (LGA) was found in 46 (10.2%). Small for gestational age (SGA) was found in 2.9%. Among 320 neonates born to GDM mothers on diet, 8 (2.5%) were SGA and 32 (10%) were LGA. Among 78 neonates born to GDM mothers on oral hypoglycemic agents, 2 (2.6%) were SGA and 12 (15.4%) were LGA. In 54 neonates born to GDM mothers on insulin, 3 (5.6%) were SGA and 2 (3.7%) were LGA. Overall, 21.7% had one or other morbidity. The overall incidence of hypoglycemia was 15.9%. Hyperbilirubinemia (34.5%) and congenital heart defects (31.8%) were the common morbidities. The other immediate morbidities included respiratory morbidities (9.7%), sepsis (3.8%), polycythemia (2%), birth injuries (1.7%) and perinatal asphyxia (0.9%). Conclusion: About 10% of neonates born to diabetic mothers have macrosomia. Macrosomia was found more in neonates born to GDM mothers who were on oral glycemic agents than those on insulin. Glucose monitoring is needed in neonates of GDM mothers to detect hypoglycemia early
dc.identifierhttps://doi.org/10.60086/jnps461
dc.identifier.urihttps://hdl.handle.net/20.500.14572/2771
dc.language.isoen_US
dc.publisherNepal Paediatric Society (JNPS)
dc.subjectNeonates
dc.subjectdiabetic mothers
dc.subjecthypoglycemia
dc.subjectimmediate morbidities
dc.subjecthyperbilirubinemia
dc.titleBirth Weight Pattern and Immediate Morbidities in 452 Neonates Born to Diabetic Mothers: A Tertiary Centre Perspective
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage149
oaire.citation.startPage143
relation.isJournalIssueOfPublication80df8ef4-6921-4877-9c01-fd57559d8c92
relation.isJournalIssueOfPublication.latestForDiscovery80df8ef4-6921-4877-9c01-fd57559d8c92
relation.isJournalOfPublication6f9be05c-05a9-4a3e-a5b5-a19a15ab042c

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