Publication:
Antibiotics Use in Hospitalised COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorThapa, Bibechan
dc.contributor.authorPathak, Samyam Bickram
dc.contributor.authorJha, Nisha
dc.contributor.authorSijapati, Milesh Jung
dc.contributor.authorShankar, Pathiyil Ravi
dc.date.accessioned2025-12-12T08:28:46Z
dc.date.available2025-12-12T08:28:46Z
dc.date.issued2022
dc.descriptionBibechan Thapa Department of Emergency Medicine, Kirtipur Hospital, Kirtipur, Kathmandu, Nepal Samyam Bickram Pathak Department of Intensive Care Unit, Nepal Mediciti Hospital, Bhaisepati, Lalitpur, Nepal https://orcid.org/0000-0001-9085-3135 Nisha Jha Department of Clinical Pharmacology, KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal https://orcid.org/0000-0003-1089-6042 Milesh Jung Sijapati Department of Internal Medicine, KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal https://orcid.org/0000-0001-6797-4764 Pathiyil Ravi Shankar IMU Center for Education, International Medical University, Bukit Jalil, Kuala Lumpur, Malaysia https://orcid.org/0000-0001-6105-5636
dc.description.abstractAbstract Introduction: Antimicrobial resistance is a global health problem. The widespread and improper antibiotics use is the leading cause of antimicrobial resistance. Bacterial co-infection in COVID-19 patients is the basis for the use of antibiotics in the management of COVID-19. COVID-19 pandemic has seriously impacted antibiotic stewardship and increased the global usage of antibiotics, worsening the antimicrobial resistance problem. The use of antibiotics among COVID-19 patients is high but there are limited studies in the context of Nepal. This study aimed to find out the prevalence of antibiotic use among hospitalised COVID-19 patients in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted on hospitalised COVID-19 patients from April 2021 to June 2021 in a tertiary care centre. Ethical approval was taken from the Institutional Review Committee (Reference number: 2078/79/05). The hospital data were collected in the proforma by reviewing the patient’s medical records during the study period of 2 months. Convenience sampling was used. Point estimate and 95% Confidence Interval were calculated. Results: Among 106 hospitalised COVID-19 patients, the prevalence of antibiotic use was 104 (98.11%) (95.52-100, 95% Confidence Interval). About 74 (71.15%) of patients received multiple antibiotics. The most common classes of antibiotics used were cephalosporins, seen in 85 (81.73%) and macrolides, seen in 57 (54.81%) patients. Conclusions: The prevalence of antibiotic use among hospitalised COVID-19 patients was found to be higher when compared to other studies conducted in similar settings.
dc.identifierhttps://doi.org/10.31729/jnma.7394
dc.identifier.urihttps://hdl.handle.net/20.500.14572/3592
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectAntibiotics
dc.subjectBacterial infection
dc.subjectCo-infection
dc.subjectCOVID-19
dc.titleAntibiotics Use in Hospitalised COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage630
oaire.citation.startPage625
relation.isJournalIssueOfPublication97a430e0-8e75-4ea0-8404-4f83f1f86a10
relation.isJournalIssueOfPublication.latestForDiscovery97a430e0-8e75-4ea0-8404-4f83f1f86a10
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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