Publication: Characteristics and Outcomes of COVID-19 Patients Admitted to Adult Intensive Care Unit: A Single-Center Observational Study from the Second Wave in Nepal
| creativeworkseries.issn | ISSN (Print) : 1993-2979 | ISSN (Online) : 1993-2987 | |
| dc.contributor.author | Pradhan, Saurabh | |
| dc.contributor.author | Upreti, Anup R | |
| dc.contributor.author | Upadhyaya, Sarobar | |
| dc.contributor.author | Oli, Manish | |
| dc.contributor.author | Shrestha, Asim | |
| dc.contributor.author | Shrestha, Yashaswi | |
| dc.date.accessioned | 2026-03-17T07:13:06Z | |
| dc.date.available | 2026-03-17T07:13:06Z | |
| dc.date.issued | 2021 | |
| dc.description | Saurabh Pradhan, Anup R Upreti, Sarobar Upadhyaya, Manish Oli, Asim Shrestha, Yashaswi Shrestha Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu, Nepal | |
| dc.description.abstract | ABSTRACT Introduction: There is inadequate data of critically ill COVID-19 caused by the delta variant. So, we sought to investigate the characteristics and outcomes during the second wave in Nepal. Methods: COVID-19 patients admitted to adult ICU of a single institution from April to August 2021 were included. Clinical, laboratory and radiological findings were collected. In-hospital mortality, length of ICU stay, duration of mechanical ventilation (MV) and complications during ICU stay were obtained. Results: Total 136 patients were included with a mean age of 56.24 (± 15.81) years and 52.2% males. Fifty-five percent had comorbidities. Mean fraction of inspired oxygen required was 0.8 and sequential organ failure assessment score on admission was 4.09. C-reactive protein (CRP), lactate dehydrogenase and ferritin levels were elevated to 62.5mg/L, 515 U/L and 472ng/mL respectively. The computed tomography score was 20. Thirty four (25%) required MV; 70 (52%) were managed with non-invasive ventilation; 41 (30.14%) required vasopressors; 4 (2.9%) required renal replacement therapy. In-hospital mortality was 43.4%. The median length of ICU stay and duration of MV were 6 and 3.5 days respectively. Hospital acquired infection was the commonest complication. Age (OR 1.126 (95% CI 1037-1.223, p value 0.005)) and CRP on admission (OR 1.023 (95% CI 1.000-1.047, p value 0.050) were found to be predictors of mortality. Conclusion: In this single center study from the second wave of the pandemic, majority of critically ill COVID-19 patients were elderly with co-existing illnesses. In-hospital mortality was high. Age and CRP on admission were found to be independently associated with poor outcome. Keywords: Characteristics, COVID-19, critical care, Nepal, outcomes | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/5180 | |
| dc.language.iso | en | |
| dc.publisher | Institute of Medicine | |
| dc.subject | Characteristics | |
| dc.subject | COVID-19 | |
| dc.subject | critical care | |
| dc.subject | Nepal | |
| dc.subject | outcomes | |
| dc.title | Characteristics and Outcomes of COVID-19 Patients Admitted to Adult Intensive Care Unit: A Single-Center Observational Study from the Second Wave in Nepal | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 77 | |
| oaire.citation.startPage | 71 | |
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