Publication: Antibiotic Usage and its Culture Sensitivity Pattern in Urinary Tract Infections at Tertiary Hospital in Eastern Nepal
Date
2017
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
The presence of microbial pathogen in the urinary tract is Urinary Tract Infection
(UTI). In BP Koirala Institute of Health Sciences (BPKIHS), each year there are around
1000 cases of UTIs. Antibiotic is empirically started after sending culture/sensitivity
(c/s) with intention to change antibiotic if c/s demands.
Objective
To see the antimicrobial prescribing pattern and c/s pattern of UTI inpatients of
BPKIHS together with their socio-demographic and laboratory profile.
Method
It was a Record-Based Retrospective Descriptive Study of past one-year. All available
inpatient-records from Medical-Record Section were extensively searched for the
keyword “UTI” diagnosis. The relevant data were entered in Microsoft Excel-sheet
and analyzed with IBM SPSS 21. Ethical clearance was obtained from the IRC before
study.
Result
There were 86 cases from four different wards. There was slight female preponderance
(51.16%). Fifty-five (63.95%) cases were complicated. Fever (75.51%) was the most
common symptom. Only 20% were tachycardic but 90% were tachypnic. Leucocytosis
(59.26%), urine albumin within 30-100 mg/dl (33.85%) and >5 Urine WBC/hpf
(80.26%) were seen. Ceftiaxone (53.16%) was the most commonly prescribed
empirical antibiotic, followed by Cefixime (6.32%). Fourteen (16.27%) cases were
culture positive. E. coli was the most (78.57%) common pathogen grown. In culture
sensitivity study, Amikacin (42.85%) was the most sensitive antibiotic.
Conclusion
Eighty-six UTI inpatients were identified last year. Fever and Tachypnoea were
very common. Leucocytosis, 1+ proteinuria and urine WBC>5/hpf were frequently
seen. Ceftriaxone was the most common antibiotic prescribed. E. coli was the most
common pathogen grown and Amikacin was the most sensitive antibiotic.
KEY WORDS
Antimicrobial, Inpatients, Urinary tract infection
Description
Panday DR, Amar A, Subedi A, Hussain Md S, Gupta M, Rauniar GP
Department of Clinical Pharmacology and Therapeutics
BP Koirala Institute of Health Sciences
Dharan, Nepal
Keywords
Antimicrobial, Inpatients, Urinary tract infection