Publication: Histiocytosis: An Uncommon Presentation with Hypopituitarism
Files
Date
2012
Article Type
Case Report
Journal Title
Journal ISSN
ISSN 1990-7974 eISSN 1990-7982
Volume Title
Pages
Pages: 81 - 84
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Langerhans cell histiocytosis is a multi system disorder with a certain predilection for involving hypothalamic pituitary axis. We hereby report a 7 year old girl presenting with polyuria, polydipsia and growth retardation. The girl had a past history of pain in right hip joint and nodular region over chest. Water deprivation test confirmed the diagnosis of central diabetes inspidus. Other investigations revealed Growth hormone deficiency and central hypothyroidism. X-ray and MRI hip revealed absent right inferior pubic ramus with bone marrow biopsy confirming the diagnosis of histiocytosis. Patient was treated with nasal Arginine Vasopressin spray, subcutaneous growth hormone and oral thyroxine.
Description
SK Kota
Department of Endocrinology, Medwin Hospital, Hyderabad, Andhra Pradesh
S Jammula
Roland Institute of Pharmaceutical Sciences Berhampur, Orisssa
PR Tripathy
Kalinga Institute of Medical Sciences Bhubaneswar, Orissa
Siva Krishna Kota
Central Security Hospital Riyadh
LK Meher
Head, Department of Medicine, MCKG Medical College, Berhampur, Orissa
K Modi
Head, Department of Endocrinology, Medwin Hospital, Hyderabad, Andhrapradesh
Keywords
Histiocytosis, Diabetes inspidus, Growth hormone deficiency, Central hypothyroidism
Identifier
https://doi.org/10.3126/jnps.v32i1.5343