Publication: Isoniazid Induced Psychosis: A Case Report Authors
Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Psychosis is a state of altered behaviour and mentation and it is not common in children. Isoniazid is a commonly used drug in the treatment and prophylaxis of tuberculosis. It may cause psychosis if overdosed but rarely with usual recommended doses. We report a case of drug induced psychosis secondary to isoniazid intake in a seven years old boy, who exhibited psychotic features about 10 days after the commencement of anti-TB combination drugs (Directly Observed Treatment Shortcourse) containing Isoniazid. This patient had no past medical or family history of mental illness. Drug induced psychosis was a possibility, and the responsible drug (isoniazid) was stopped. He improved following the withdrawal of isoniazid. Isoniazid psychosis is a major complication as iatrogenic psychiatric complications can greatly impact the patients’ quality of life, which if recognised early can be effectively treated.
Author Biographies
Taranjeet Kaur, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
Department of Paediatrics
Kanwalpreet Kaur, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
Department of Paediatrics
Preeti Malhotra, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
Department of Paediatrics
Description
Taranjeet Kaur
Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
Kanwalpreet Kaur
Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
Preeti Malhotra
Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
Keywords
adverse effects, isoniazid, psychosis, tuberculosis