Publication: Efficacy of Probiotic Saccharomyces boulardii as an Adjuvant Therapy in Acute Childhood Diarrhoea
| creativeworkseries.issn | ISSN 1990-7974 eISSN 1990-7982 | |
| dc.contributor.author | Dash, Dillip Kumar | |
| dc.contributor.author | Dash, Mrutunjaya | |
| dc.contributor.author | Mohanty, M.D. | |
| dc.contributor.author | Acharya, Naresh | |
| dc.date.accessioned | 2026-02-23T08:25:34Z | |
| dc.date.available | 2026-02-23T08:25:34Z | |
| dc.date.issued | 2016 | |
| dc.description | Dillip Kumar Dash IMS and SUM Hospital, Bhubaneswar Mrutunjaya Dash IMS and SUM Hospital, Bhubaneswar M.D. Mohanty IMS and SUM Hospital, Bhubaneswar Naresh Acharya IMS and SUM Hospital, Bhubaneswar | |
| dc.description.abstract | Abstract: Introduction: Administration of S. boulardii in addition to rehydration therapy in diarrhea found to be beneficial in many aspects owing to a variety of causes and importantly it is was not associated with any adverse effects. Material and Methods: We conducted a prospective study of children suffering from acute diarrhoea, at a private tertiary care hospital. Children were divided into 2 groups randomly as per odd(Group 1 ) and even (Group 2) bed allotted in indoor at the time of admission: Group 1 included children on oral rehydration therapy (ORT) + Zinc + Saccharomyces boulardii (Probiotic 5 billion CFU twice daily) and Group 2 comprised of children on ORT+ Zinc. Our objective was to systematically review data on the effect of S. boulardii on acute childhood diarrhoea. Results: Out of a total of 126 children less than 2 years, 2-6 years and 6-14 years were 72 (57.14%), 42(33.33%) and 12(09.52%) respectively. The duration of diarrhoea in Group 1 was 26.31 hours and Group 2 was 47.81 hours (p<0.01). The frequency of diarrhoea showed improvement within 24 and 72 hours in Group 1 and Group 2 respectively (p<0.01).Similarly, the mean duration of hospital stay was 2.68 days in Group 1 and 4.8 days in Group 2.The treatment cost was INR 850 and INR 1650 while social cost was INR 1250 and 2600 in Group 1 and 2 respectively. Conclusion:This study shows that S. boulardii reduced the duration, frequency and hospital stay of diarrhoea thereby reducing the treatment and social costs. | |
| dc.identifier | https://doi.org/10.3126/jnps.v36i3.15539 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/4864 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Paediatric Society (JNPS) | |
| dc.subject | Childhood diarrhoea | |
| dc.subject | Saccharomyces boulardii | |
| dc.subject | therapy | |
| dc.title | Efficacy of Probiotic Saccharomyces boulardii as an Adjuvant Therapy in Acute Childhood Diarrhoea | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 255 | |
| oaire.citation.startPage | 250 | |
| relation.isJournalIssueOfPublication | 0692fd39-d464-4878-b0ff-743d5b445183 | |
| relation.isJournalIssueOfPublication.latestForDiscovery | 0692fd39-d464-4878-b0ff-743d5b445183 | |
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