Article:
Frequency and risk factors for intradialytic hypotension in patients undergoing maintenance hemodialysis

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creativeworkseries.issnOnline ISSN: 2676-1424; Print ISSN: 2676-1319
dc.contributor.authorYogi, Rubash Nath
dc.contributor.authorChhetri, Pramod Kumar
dc.contributor.authorManandhar, Dhiraj Narayan
dc.contributor.authorYogi, Rusmrita
dc.contributor.authorUpreti, Anup Raj
dc.contributor.authorSingh, Anurag Prasad
dc.contributor.authorGiri, Prapti
dc.creator.affiliationDepartment of Nephrology and Transplant Medicine, Shahid Dharmabhakta National Transplant Center, Bhaktapur
dc.creator.affiliationDepartment of Nephrology, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Nephrology, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationMedical Officer, Motherland Hospital, Pepsicola, Kathmandu
dc.creator.affiliationDepartment of Nephrology and Transplant Medicine, Shahid Dharmabhakta National Transplant Center, Bhaktapur
dc.creator.affiliationDepartment of Community Programs, Dhulikhel Hospital, Kathmandu University, Dhulikhel, Kavre
dc.date.accessioned2026-09-21T10:07:04Z
dc.date.available2026-09-21T10:07:04Z
dc.date.issued2026
dc.description.abstractAbstract: Hemodialysis (HD) patients and providers have long struggled with intra-dialytic hypotension (IDH), a complication that continues to challenge the safety and effectiveness of HD. IDH is associated with chronic end-organ damage and remains an independent risk factor for mortality among HD patients. Persistent hemodynamic instability may also accelerate the decline of residual renal function, further worsening clinical outcomes. Because individuals on dialysis already face markedly increased cardiovascular mortality and morbidity, identifying the prevalence and contributing factors of IDH has become an important clinical and academic priority. This observational study was carried out in the Hemodialysis Unit of Nepal Medical College and Teaching Hospital over one year (Baishakh 2079 to Chaitra 2079 B.S, April 2022 to March 2023 AD) without interventions or the collection of patient material. Ethical approval was obtained from the Institutional Review Committee. During each dialysis session, patients were assessed for pre- and post-dialysis weight, blood pressure, and heart rate at multiple intervals, ultrafiltration volume, and any clinical events or medical interventions related to intra-dialytic hypotension. A total of 110 patients participated, contributing 5,232 dialysis sessions. The incidence of IDH varied widely depending on the definition used, measuring 14.47% and 9.42% under stricter criteria, and rising to 62.8% with a more liberal definition. Although HD remains a widely used and generally safe modality, complications such as IDH persist and can be life-threatening. As complications and their associated factors continue to change over time, a more vigilant and systematic approach is needed to identify, monitor, and address them effectively. This highlights the need for ongoing evaluation in HD practice.
dc.identifier.doihttps://doi.org/10.3126/nmcj.v28i2.97645
dc.identifier.urihttps://hdl.handle.net/20.500.14572/7788
dc.language.isoen_US
dc.publisherNepal Medical College Pvt. Ltd.
dc.subjectChronic kidney disease
dc.subjectHemodialysis
dc.subjectIntradialytic hypotension
dc.titleFrequency and risk factors for intradialytic hypotension in patients undergoing maintenance hemodialysis
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage95
oaire.citation.startPage91
relation.isJournalIssueOfPublication7343f6a1-de6b-4f54-9249-346798b158af
relation.isJournalIssueOfPublication.latestForDiscovery7343f6a1-de6b-4f54-9249-346798b158af
relation.isJournalOfPublication865934c8-5e95-468c-8ca6-7bb2529e4064

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