Publication:
Rickettsial Infection amongst Febrile Illness Patient in a Tertiary Care Hospital: A Retrospective Cross-sectional Study

creativeworkseries.issn1812-2027
dc.contributor.authorGurung, RB
dc.contributor.authorSapkota, P
dc.contributor.authorBhatt, S
dc.contributor.authorTamang, A
dc.contributor.authorJoshi, S
dc.contributor.authorKhadka, S
dc.contributor.authorJaisy, DN
dc.contributor.authorChalise, S
dc.contributor.authorShrestha, P
dc.date.accessioned2025-12-26T08:44:59Z
dc.date.available2025-12-26T08:44:59Z
dc.date.issued2022
dc.descriptionGurung RB,1*Sapkota P,1*Bhatt S,1Tamang A,1JoshiS,1 Khadka S,1 Jaisy DN,1 Chalise S,1 Shrestha P2 1Department of Internal Medicine 2Department of Public Health and Community Programs Dhulikhel Hospital, Kathmandu University Hospital Kathmandu University School of Medical Sciences Dhulikhel, Kavre, Nepal
dc.description.abstractABSTRACT Background Rickettsial infection is an emerging neglected tropical disease in the Southeast Asia. In past few years Nepal is also reporting escalating prevalence of rickettsia. The under evaluation is resulting it as undiagnosed or are simply labeled as pyrexia of unknown origin. Objective To find out the prevalence of rickettsia in a hospital setting, assess the socio- demographic and other relevant clinical features of the rickettsia patients. Method This is a hospital based retrospective cross-sectional study from October 2020 to October 2021. This study reviewed the medical records of the department. Result The study included 105 eligible patients and the prevalence rate was 4.38 per 100 patients. The mean age of the participants was 42 years, and the mean hospital stay was 3 (SD ±2.06) days. More than 55% of the participants had fever for less than or equal to 5 days and 9% had Eschar present. Vomiting, headache, and myalgia were the most common symptoms and hypertension, and diabetes were the common comorbidities. Pneumonia and the acute kidney injury were the two complications of the patients as stated in the study. The severity of the thrombocytopenia deducted from admission time to discharge, and the case fatality was 4%. Conclusion The future studies shall consider on collaborative clinical and entomological research. This would help in better understanding of the etiology of supposedly unknown febrile illness and the under-investigated field of emerging rickettsia in Nepal. KEY WORDS Eschar, Febrile illness, IgM titer, Rickettsia, Thrombocytopenia
dc.identifier.urihttps://hdl.handle.net/20.500.14572/3883
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectEschar
dc.subjectFebrile illness
dc.subjectIgM titer
dc.subjectRickettsia
dc.subjectThrombocytopenia
dc.titleRickettsial Infection amongst Febrile Illness Patient in a Tertiary Care Hospital: A Retrospective Cross-sectional Study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage371
oaire.citation.startPage366
relation.isJournalIssueOfPublication70955ae5-defd-4f34-89b2-a5dc24ab2d4d
relation.isJournalIssueOfPublication.latestForDiscovery70955ae5-defd-4f34-89b2-a5dc24ab2d4d
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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