Publication:
Non-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorGhartimagar, Dilasma
dc.contributor.authorShrestha, Manish Kiran
dc.contributor.authorJhunjhunwala, Adarsh
dc.contributor.authorGhosh, Arnab
dc.contributor.authorThapa, Sushma
dc.contributor.authorRegmi, Sudeep
dc.contributor.authorTalwar, Om Praksah
dc.date.accessioned2026-02-13T08:43:28Z
dc.date.available2026-02-13T08:43:28Z
dc.date.issued2021
dc.descriptionDilasma Ghartimagar Department of Pathology, Manipal College of Medical Science, Pokhara, Nepal Manish Kiran Shrestha Department of Radiology, Charak Medical Hospital, Pokhara, Nepal Adarsh Jhunjhunwala Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal. https://orcid.org/0000-0001-5501-5849 Arnab Ghosh Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal. https://orcid.org/0000-0002-8566-2067 Sushma Thapa Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal. https://orcid.org/0000-0002-1303-9065 Sudeep Regmi Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal. https://orcid.org/0000-0002-3207-515X Om Praksah Talwar Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal. https://orcid.org/0000-0002-5120-6565
dc.description.abstractAbstract: Introduction: Gallbladder diseases are prevalent worldwide and present with a diverse histopathological spectrum. Mucosal irritation and chronic inflammation is considered as an important etiological factor for the mechanical or functional dysfunction of emptying of the gallbladder. This study aims to find the prevalence of non-neoplastic lesions of gallbladder among cholecystectomy specimens of a tertiary care center. Methods: A descriptive cross-sectional study was conducted in the Department of Pathology, of a tertiary care center from January 2005 to December 2020. Ethical approval was taken from the Institutional Review Committee. All the patients who had undergone cholecystectomy procedures which showed non-neoplastic lesions were enrolled in the study. Convenient sampling was done. Statistical Package for Social Sciences version 21 and Microsoft Excel were used for data analysis. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Out of 4914 cholecystectomy specimens, 4852 (98.73%) (95% Confidence Interval= 98.42- 99.04) were non-neoplastic lesions. There were 1252 (25.8%) males and 3600 (74.2%) females with a male to female ratio of 1:2.87. Age ranged from 2 to 89 years with a mean age of 45±14.48 years. Gallbladder lesions were observed maximum in age group 41-50 years with 1200 (24.7%) cases. Among the non-neoplastic lesions, cholecystitis without any specific finding was the most common finding with 3028 (62.4%) cases followed by cholelithiasis with 1478 (30.5%) cases. Conclusions: The prevalence of non-neoplastic lesions of gallbladder is similar to other studies done in similar setings. Female predominance was noted in non-neoplastic lesions.
dc.identifierhttps://doi.org/10.31729/jnma.5861
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4748
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectcholecystitis
dc.subjectcholelithiasis
dc.subjectgallbladder
dc.subjectmetaplasia
dc.subjectpyloric
dc.titleNon-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage974
oaire.citation.startPage970
relation.isJournalIssueOfPublicationed1eeb6e-9806-4484-8f37-8cdbad701272
relation.isJournalIssueOfPublication.latestForDiscoveryed1eeb6e-9806-4484-8f37-8cdbad701272
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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