Publication:
Vitamin D Deficiency among Blood Transfusion-Dependent Beta Thalassemia Children Admitted to Tertiary Level Pediatric Hospital in Nepal: A Descriptive Cross-Sectional Study

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorShrestha,Anil Kumar
dc.contributor.authorSherpa, Sangay Chultim
dc.contributor.authorGyawali, Bindu
dc.contributor.authorSharma, Manisha
dc.contributor.authorAdhikari, Santosh
dc.contributor.authorShrestha, Suchitra
dc.contributor.authorBhattarai, Susan
dc.contributor.authorThapa, Sagar
dc.contributor.authorSharma, Devashish
dc.contributor.authorPaudel, Prajwal
dc.contributor.authorGyawali, Sushil
dc.date.accessioned2025-07-31T06:49:02Z
dc.date.available2025-07-31T06:49:02Z
dc.date.issued2024
dc.descriptionAnil Kumar Shrestha Department of Pediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal Sangay Chultim Sherpa Department of Medicine, Om Hospital and Research Center, Chabahil, Kathmandu, Nepal Bindu Gyawali Curative Service Division, Ministry of Health and Population, Teku, Kathmandu, Nepal Manisha Sharma Department of Pediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal Santosh Adhikari Department of Pediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal Suchitra Shrestha Nepalese army Institute of Health Science, Bhandarkhal, Kathmandu, Nepal Susan Bhattarai Department of Pediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal Sagar Thapa Nepalese army Institute of Health Science, Bhandarkhal, Kathmandu, Nepal Devashish Sharma Department of Pediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal Prajwal Paudel Department of Pediatrics, Paropakar Maternity & Women’s Hospital, Thapathali, Kathmandu, Nepal Sushil Gyawali Department of Pediatric Surgery, Kanti Children’s Hospital, Maharajgunj,Kathmandu, Nepal
dc.description.abstractAbstract Introduction: Children with beta thalassemia are on regular blood transfusions, which could result in iron deposition in the liver causing decreased synthesis of Vitamin D-25OH. There are limited publications on the association of Vitamin D deficiency with blood transfusion-dependent thalassemia in the Nepalese population. This study aims to determine the prevalence of Vitamin D deficiency among blood transfusion-dependent beta-thalassemia patients. Methods: This was a descriptive cross-sectional study conducted among beta-thalassemia major patients under 15 years of age, receiving regular blood transfusion, from July 17, 2022, to July 16, 2023, after attaining ethical approval from Ethical Review Committee, (reference number 155). Data were collected using convenience sampling, and descriptive analyses were performed using Microsoft Excel and Statistical Package for Social Sciences (SPSS) 2024. Results: A total of 127 blood transfusion-dependent beta-thalassemia major patients were included in the study, of whom 82 (64.56%) were female. Among these patients, 104 (81.88%) were aged between 5 and 14 year. Among 127, 41 (32.28%) had Vitamin D insufficiency, and 31 (24.40%) had Vitamin D deficiency. There were 12 (9.44%) underweight children. Conclusions: Vitamin D deficiency was seen in more than half of the children with blood transfusion dependent beta thalassemia major.
dc.identifierhttps://doi.org/10.31729/jnma.8779
dc.identifier.urihttps://hdl.handle.net/20.500.14572/1037
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.titleVitamin D Deficiency among Blood Transfusion-Dependent Beta Thalassemia Children Admitted to Tertiary Level Pediatric Hospital in Nepal: A Descriptive Cross-Sectional Study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage626
oaire.citation.startPage621
relation.isJournalIssueOfPublication1a7d80e7-5c12-4308-bd44-1ce4c4bf8556
relation.isJournalIssueOfPublication.latestForDiscovery1a7d80e7-5c12-4308-bd44-1ce4c4bf8556
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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