Publication: Clinical Efficacy of Subgingivally Delivered Punica Granatum Chip and Gel in Management of Chronic Periodontitis Patients
Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Periodontitis has a multifactorial etiology, and the pathogenic bacteria that reside in
the subgingival area are the primary etiologic agent.
Objective
The study aimed to evaluate the clinical efficacy and benefits of herbal chip and gel
made from extracts of Punica granatum as a subgingival adjunct to scaling and root
planing (SRP).
Method
A randomized control clinical trial was conducted on 30 systemically healthy patient’s
sites having chronic periodontitis, and they were randomly allocated to into three
treatment groups followed by Scaling and Root Planing in all patients. Group 1 - Ten
patients received Scaling and Root Planing and Punica granatum chip at selected sites.
Group 2 - Ten patients received Scaling and Root Planing and punica granatum gel at
selected sites. Group 3 - Ten patients with Scaling and Root Planing alone. Clinical
parameters were recorded at baseline, 21 days and at 45 days which included plaque
index (PI), gingival index (GI), probing pocket depth (PPD) and relative attachment
level (RAL).
Result
Plaque Index and Gingival index showed better reduction in group I compared to
group II and group III at 21st day 45th day follow up. Analysing Pocket Probing Depth
the intergroup comparison revealed similar results with maximum reduction being
seen in group I from baseline to 21 and baseline to 45 days (p < 0.001). On analysing
Relative Attachment Loss revealed reduction in all three groups with maximum
reduction in group I from baseline to 45 days and reduction in group III was not
statistically significant (p < 0.090).
Conclusion
The study concluded that Punica granatum chip as an adjunct to Scaling and Root
Planing was more effective than Punica granatum gel and scaling and root planing
alone.
KEY WORDS
Hydrolysable tannins, Periodontal regeneration, Punica granatum, Relative
attachment level, Subgingival drug delivery
Description
Tyagi P,1 Dodwad VM,2 Vaish S,3 Chowdhery T,3 Gupta N,1 Kukreja JB4
1Department of Periodontology and Oral Implantology,
Shri Bankey Bihari Dental College,
2Department of Periodontology and Oral Implantology,
BVP Sangli,
3Department of Periodontology and Oral Implantology,
I.T.S Dental College, Muradnagar, Ghaziabad,
4Department of Periodontology and Oral Implantology,
Teerthanker Mahaveer Dental College and ResearchCenter, Moradabad, India.
Keywords
Hydrolysable tannins, Periodontal regeneration, Punica granatum, Relative attachment level, Subgingival drug delivery