Publication:
Incidence and Outcomes of Re-Exploration in Adult Cardiac Surgery at A Tertiary Care Hospital

creativeworkseries.issnISSN (Print) : 1993-2979 | ISSN (Online) : 1993-2987
dc.contributor.authorPradhan, Ashok
dc.contributor.authorPokharel, Rojina
dc.contributor.authorKadel, Prashiddha B
dc.contributor.authorBashyal, Krishna prashad
dc.contributor.authorKhakural, Prabhat
dc.contributor.authorBaral, Ravi K
dc.contributor.authorBhattarai, Anil
dc.contributor.authorKoirala, Bhagawan
dc.date.accessioned2026-02-23T06:39:18Z
dc.date.available2026-02-23T06:39:18Z
dc.date.issued2023
dc.descriptionAshok Pradhan, Rojina Pokharel, Prashiddha B Kadel, Krishnaprashad Bashyal, Prabhat Khakural, Ravi K Baral, Anil Bhattarai, Bhagawan Koirala Department of Cardiothoracic Vascular Surgery, Maharajgunj Medical Campus, Manmohan Cardiothoracic vascular and Transplant Centre, Institute of Medicine, Maharajgunj, Kathmandu, Nepal
dc.description.abstractABSTRACT Introduction: Postoperative bleeding is a significant complication following cardiac surgery, with a global re-exploration incidence of 2-5%. This study aims to investigate re-exploration rates, risk factors, and outcomes within the unique context of a tertiary care center in Nepal. Methods: In this retrospective, single-center study, we analyzed all consecutive adult patients (≥18 years) who underwent cardiac surgery with cardiopulmonary bypass (CPB) at the Manmohan Cardiothoracic Vascular and Transplant Centre (Nepal) between 2018-2021. Data on demographics, clinical characteristics, operative details, re-exploration, and outcomes were extracted from medical records. Statistical analysis included descriptive statistics, chi-square tests, independent samples t-tests, and logistic regression. Results: Of 720 patients, 56 (7.8%) required re-exploration for bleeding. Emergency procedures were strongly associated with higher re-exploration (p<0.05). Non-surgical bleeding was the primary cause in 42.9% of cases. Independent risk factors included preoperative deranged LFTs (OR=2.1, 95% CI: 1.2-3.7), elevated creatinine (>1.5 mg/dL, OR= 3.2, 95% CI: 1.8-5.6), prolonged CPB time (>120 min), and substantial transfusion requirements. Modified Bentall's procedures had the highest re-exploration rate (21.4%). Re-explored patients experienced higher AKI rates (87.5%), longer hospitalizations (13.6 vs. 7.2 days, p<0.001), and increased in-hospital mortality confined to emergency cases (1.94%). Conclusion: Emergency procedures had higher rate of re-exploration. Preoperative deranged LFTs, elevated creatinine, prolonged CPB time, and substantial transfusion requirements were independent risk factors for re-exploration. Re-explored cases experienced higher complication. In-hospital mortality were confined to emergency cases only. Keywords: Bleeding; cardiac surgery; emergency surgery; modified Bentall’s procedure; re-exploration
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4845
dc.language.isoen_US
dc.publisherInstitute of Medicine
dc.subjectBleeding
dc.subjectcardiac surgery
dc.subjectemergency surgery
dc.subjectmodified Bentall’s procedure
dc.subjectre-exploration
dc.titleIncidence and Outcomes of Re-Exploration in Adult Cardiac Surgery at A Tertiary Care Hospital
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage24
oaire.citation.startPage21
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relation.isJournalOfPublicationa9ba45d9-ee33-4a6b-b1fc-6626b87eec6c

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