Publication: New-Onset Diabetes after Transplant (NODAT)
Date
2014
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
New onset diabetes mellitus after transplantation (NODAT) is a well known
complication following solid organ transplantation and has been reported to
occur in 4% to 25% of renal transplant recipients, 2.5% to 25% of liver transplant
recipients, hepatitis C virus (HCV) infection between 40% and 60% and 2% to 53% of
all solid organ transplants. This variation in the reported incidence may be because
of lack of a universal agreement on the definition of NODAT, the duration of follow-
up, and the presence of modifiable and non-modifiable risks factors. Moreover,
reduced patient survival and accelerated graft loss have been reported with NODAT.
In our country also there is increasing in number of kidney transplants patients and
along with that there is chance of development of NODA. It is better to detect the
NODATS early. So in this article I tried to presents an overview of the literature on
the current diagnostic criteria for NODAT and discuss suggested risk factors for the
development of NODAT, its potential pathogenic mechanisms, and its impact on
post-transplant outcomes after solid organ transplantation.
KEYWORDS
New onset diabetes after transplantation, review and management
Description
Maskey R
Department of Internal Medicine
BPKIHS, Dhran, Nepal
Keywords
New onset diabetes after transplantation, Review and management