Publication:
Sensitivity and Specificity of Ankle Brachial Index for Diagnosis of Peripheral Arterial Disease in Diabetic Patients Presenting to University Hospital of Nepal

creativeworkseries.issn1812-2027
dc.contributor.authorKarmacharya, RM
dc.contributor.authorVaidya, S
dc.contributor.authorYadav, B
dc.contributor.authorSharma, S
dc.contributor.authorBhatt, S
dc.contributor.authorBhandari, N
dc.contributor.authorBhandari, S
dc.contributor.authorMaharjan, S
dc.contributor.authorBhusal, J
dc.date.accessioned2026-01-27T07:51:52Z
dc.date.available2026-01-27T07:51:52Z
dc.date.issued2025
dc.descriptionKarmacharya RM, Vaidya S, Yadav B, Sharma S, Bhatt S, Bhandari N, Bhandari S, Maharjan S, Bhusal J Department of Surgery Cardio Thoracic and Vascular Surgery Unit Dhulikhel Hospital, Kathmandu University Hospital Kathmandu University School of Medical Sciences Dhulikhel, Kavre, Nepal
dc.description.abstractABSTRACT Background Diabetes is a significant risk factor for peripheral arterial disease (PAD) that increases morbidity and mortality. Hence, early detection of peripheral arterial disease is necessary. Evidence shows Ankle Brachial Index (ABI) as a promising test to diagnose peripheral arterial disease. However, sensitivity and specificity need to be evaluated before clinical use. Objective To determine Ankle Brachial Index sensitivity and specificity for the diagnosis of peripheral arterial disease in diabetic patients. Method Diabetic patients were recruited from Dhulikhel Hospital. Doppler ultrasonography (DUS) was done in all the recruited participants and peripheral arterial disease was assessed. Based on Jager’s criteria, those with grade III and IV stenosis were diagnosed as peripheral arterial disease and underwent ankle brachial index. Ankle brachial indexscores below 0.9 and above 1.5 were considered abnormal. The diagnosis by ankle brachial index was matched against the gold standard doppler ultrasonography to determine its specificity and sensitivity. Descriptive statistics and independent t-tests were used for statistics. P-value < 0.05 was considered statistically significant. Result There were total of 237 diabetic patients of which 31.2% had peripheral arterial disease. We found high sensitivity and specificity of ankle brachial index when tested against doppler ultrasonography with the values ranging from 88.68-89.66% and 86.67-90% respectively. Conclusion Ankle brachial index can be used in clinical settings to diagnose peripheral arterial disease in individuals with diabetes mellitus. KEY WORDS Ankle brachial index, Diabetes, Peripheral arterial disease, Sensitivity, Specificity
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4390
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectAnkle brachial index
dc.subjectDiabetes
dc.subjectPeripheral arterial disease
dc.subjectSensitivity
dc.subjectSpecificity
dc.titleSensitivity and Specificity of Ankle Brachial Index for Diagnosis of Peripheral Arterial Disease in Diabetic Patients Presenting to University Hospital of Nepal
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage336
oaire.citation.startPage333
relation.isJournalIssueOfPublicationf0051982-71eb-4487-affd-f30474a1df9f
relation.isJournalIssueOfPublication.latestForDiscoveryf0051982-71eb-4487-affd-f30474a1df9f
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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