Publication: Nail Changes Following Valproate Therapy
Date
2024
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Valproic acid is a widely prescribed medication for seizure disorders, mood
disorders, and migraines. The adverse effects involving nails following the use of
sodium valproate are rare. The nail changes reported so far include onycholysis,
onychomadesis, the roughness of the nail, brownish-yellow discoloration, and a
transverse yellow band. These changes are independent of the age of the patients,
dose, and duration of medication. The nail changes are reversible following the
discontinuation of the medication.
KEY WORDS
Onycholysis, Onychomadesis, Nail discoloration, Valproic acid
Description
Shrestha S,1 Pandey A,2 Pathak R3
1Department of Dermatology
Rapti Province Hospital
Dang, Tulsipur, Nepa
2Kathmandu University School of Medical Sciences
Dhulikhel Hospital, Kathmandu University Hospital
Dhulikhel, Kavre, Nepal
3Department of Dermatology
Pokhara Academy of Health Sciences
Pokhara, Nepal
Keywords
Onycholysis, Onychomadesis, Nail discoloration, Valproic acid