Publication:
Histopathological Study of Skin Lesions in a Tertiary Care Hospital: A Descriptive Cross-sectional Study

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorChalise, Sanat
dc.contributor.authorDhakhwa, Ramesh
dc.contributor.authorPradhan, Sailesh Bahadur
dc.date.accessioned2026-08-13T05:39:23Z
dc.date.available2026-08-13T05:39:23Z
dc.date.issued2020
dc.descriptionSanat Chalise Department of Pathology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal Ramesh Dhakhwa Department of Pathology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal Sailesh Bahadur Pradhan Department of Pathology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
dc.description.abstractAbstract Introduction: Skin diseases are much common in developing countries. The spectrum varies according to geographic distribution, gender, age, and coexisting disorder. We conducted this study to find out the prevalence of different skin lesions and to evaluate their frequency and site of distribution. Methods: A descriptive cross-sectional study was done in the pathology department of Kathmandu Medical college from June 2019 to November 2019 after ethical clearance. The skin biopsies were processed, sectioned and stained with Haematoxylin and eosin and evaluated. A convenience sampling method was used. Data was collected and entry was done in Statistical Packages for Social Services version 20.0, point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Among 133 skin biopsies examined, noninfectious vesicobullous and vesicopustular disease were found in 42 (46.6%) cases followed by microbial disease in 22 (24.5%) and noninfectious erythematous papular and squamous disease in 21 (23.4%) cases. Spongiotic dermatitis was the most common vesicobullous disease seen in 26 (28.9%) cases. Leprosy was the commonest microbial disease found in 7 (7.8%) cases. The commonest noninfectious erythematous papular and squamous disease was erythema dyschromicum perstans seen in 7 (7.8%) cases. The commonest neoplastic lesion was keratinocytic tumor seen in 12 (32.5%) cases. The commonest tumor of the skin was intradermal nevus seen in 6 (16.3%) cases. Conclusions: Spongiotic dermatitis is a predominating non-neoplastic and overall skin lesion which was similar to the other studies done. Histopathological examination is the gold standard for the proper diagnosis as histomorphological features distinguish various skin lesions. Keywords: dermatitis; papular; tumors.
dc.identifierhttps://doi.org/10.31729/jnma.4799
dc.identifier.urihttps://hdl.handle.net/20.500.14572/7270
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectdermatitis
dc.subjectpapular
dc.subjecttumors
dc.titleHistopathological Study of Skin Lesions in a Tertiary Care Hospital: A Descriptive Cross-sectional Study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage222
oaire.citation.startPage218
relation.isJournalIssueOfPublication39604197-9acd-4725-aa54-021b972ac436
relation.isJournalIssueOfPublication.latestForDiscovery39604197-9acd-4725-aa54-021b972ac436
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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