Publication: Outcome of Surgical Resection of Craniopharyngioma: Single Center 12 Years’ Experience
| creativeworkseries.issn | 1812-2027 | |
| dc.contributor.author | Bishokarma, S | |
| dc.contributor.author | Shrestha, S | |
| dc.contributor.author | Ranabhat, K | |
| dc.contributor.author | Koirala, S | |
| dc.contributor.author | Shrestha, D | |
| dc.contributor.author | Panth, R | |
| dc.contributor.author | Gongal, DN | |
| dc.date.accessioned | 2025-11-25T07:11:14Z | |
| dc.date.available | 2025-11-25T07:11:14Z | |
| dc.date.issued | 2018 | |
| dc.description | Bishokarma S,1 Shrestha S,1 Ranabhat K,2 Koirala S,1 Shrestha D,1 Panth R,3 Gongal DN1 1Department of Neurosurgery 2Department of Radiologist 3Department of Pathology Upendra Devkota Memorial National Institute of Neurological and Allied Sciences Bansbari, Kathmandu, Nepal | |
| dc.description.abstract | ABSTRACT Background Craniopharyngiomas (CPs) are rare epithelial tumors arising from the Rathke’s pouch remnant located along the path of the craniopharyngeal duct accounting for 1.2-4% of all primary intracranial brain tumors, the primary treatment of which is surgery. Objective Whether radical surgical resection or partial resection followed by radiotherapy is a topic of debate. We presented our 12 years single center experience on surgical resection of craniopharyngioma. Method This was a descriptive cross-sectional study conducted among forty-five patients who underwent transcranial resection of craniopharyngioma during a period of 12 years. Data were collected from medical record archives. Glassgow outcome score (GOS), electrolyte imbalance and visual complications were assessed as outcome measure. GOS > 3 was considered favorable while score ≤ 3 was considered unfavorable. Recurrence of tumors were analyzed. Result Out of 45 patients, 28 patients were male with male to female ration of 1.64. Mean age was 32.22±16.42 years. Supra-sellar craniopharyngioma were the most common location. Gross total resection was accomplished in 32 patients (71.1%) while subtotal resection among 13 patients (28.9%). Post-operative Diabetes Insipidus was developed among 35 patients (77.7%). Adamantinomatous craniopharyngioma was the most common histopathological type. Postoperative MRI with contrast was repeated to ascertain the completeness of resection. All patient with subtotal resection received radiotherapy. Follow up period ranged from 3 months to 8 years with mean of 4.2 years. Favorable outcome (GOS>3) was seen among 41 patients while unfavorable among 4 patients. Recurrence seen among 4 patients (8.9%). Overall mortality was 4 (8.8%). Conclusion Gross total excision of craniopharyngioma has a favorable outcome with acceptable morbidity. KEY WORDS Adamantinomatous, Craniopharyngioma, Pterional craniotomy, Radiation therapy | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/3251 | |
| dc.language.iso | en_US | |
| dc.publisher | Kathmandu University | |
| dc.subject | Adamantinomatous | |
| dc.subject | Craniopharyngioma | |
| dc.subject | Pterional craniotomy | |
| dc.subject | Radiation therapy | |
| dc.title | Outcome of Surgical Resection of Craniopharyngioma: Single Center 12 Years’ Experience | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 332 | |
| oaire.citation.startPage | 328 | |
| relation.isJournalIssueOfPublication | 423e774f-9346-4d4b-95c6-39a03dfcc60b | |
| relation.isJournalIssueOfPublication.latestForDiscovery | 423e774f-9346-4d4b-95c6-39a03dfcc60b | |
| relation.isJournalOfPublication | a782b7ff-cf89-4178-ad1c-11ed89cfe1bd |