Publication: Adult-onset Still's Disease: A Case Report
Date
2020
Article Type
Case Report
Journal Title
Journal ISSN
JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
Volume Title
Pages
Pages: 115 - 118
Publisher
Nepal Medical Association
Abstract
Abstract
Adult-onset Still’s Disease is a rare auto inflammatory disorder of unknown etiology characterized mainly by high spiking fever, arthritis, evanescent rash and lymphadenopathy. It is a form of systemic onset juvenile rheumatoid arthritis that is encountered in adults, typically between 15-25 years and 36-45years. We here describe a 28 years lady with fever, arthritis of multiple large joints, lymphadenopathy and rash, with negative Rheumatoid factor and evidence of past infection with Ebstein-Barr virus and Parvovirus B19. History, examination findings and investigations showed several features consistent with adult-onset Still’s disease along with high ferritin level. After exclusion of probable other diagnosis and use of Yamaguchi criteria, she was diagnosed with adult-onset Still’s disease. All the major and minor criteria of Yamaguchi for diagnosis were met. Her disease responded well with steroid, she achieved remission and is currently under maintenance therapy.
Keywords: Adult-onset stills disease; arthritis; ferritin; fever.
Description
Ashok Sapkota
Department of Medical Oncology, B.P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal
Nirdesh Pokhrel
Department of Medical Oncology, B.P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal
Jayaram Adhikari
Department of Medical Oncology, B.P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal
Bishal Shrestha
Department of Internal Medicine, Bharatpur Samudayik Hospital, Bharatpur, Nepal
Yoveen Kumar Yadav
Tuberculosis Care and Control Project, Nepal CRS Company, Kathmandu, Nepal
Keywords
Adult-onset stills disease, arthritis, ferritin, fever
Identifier
https://doi.org/10.31729/jnma.4844