Publication: Primary vesicoureteric reflux in Nepalese children
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Date
2008
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Journal ISSN
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Publisher
Kathmandu University
Abstract
Abstract
Background: Vesicoureteric reflux (VUR) is a common urinary tract abnormality observed in children with
urinary tract infection and children with VUR are at risk of reflux nephropathy and renal parenchymal damage.
In Nepal, till date there are no published series of VUR in children.
Aims and Objectives: To study the incidence of VUR in Nepalese children with Urinary tract infection (UTI),
to analyze the age and sex wise distribution and clinical course of children with VUR together with the rate of
spontaneous resolution of VUR in children
Methodology: A retrospective hospital based study conducted at Department of Paediatrics Patan Hospital from
June 2002 to December 2005. Hospital record files of all the children undergoing micturating
cystourethrography (MCUG) as part of UTI work up were traced and the files of children with positive VUR
were separated and analyzed.
Results: Over the 3 and a half years study period total 145 micturating cystourethrograph were done in children
with UTI, out of which 35(24%) were positive for VUR. Among the children with VUR, the most common age
group was between two to twelve months and the male female ratio was 1.2:1.More than 60% had bilateral
VUR and bilateral grade II VUR was the most common finding. Renal scan (DMSA) was done in only 5 cases
and out of those two showed renal scaring. Eight cases underwent repeat MCUG after 1-1 ½ years and
spontaneous resolution of VUR was seen in 5 (62.5%) cases. Six cases were lost in follow up, 5 cases went for
surgical intervention.
Conclusion: The incidence of VUR in children with UTI in our part is almost comparable to western data.
Children with VUR need regular and long term follow-up.
Key words: Vesicoureteric reflux (VUR), Micturating cystourethrography (MCUG), Reflux nephropathy,
Nepalese children, Patan Hospital
Description
Shrestha S1, Basukala S2, Pokhrel N3
1Consultant Paediatrician, 2Chief, Department of Radiology, 3Resident, Patan hospital, Lalitpur, Nepal