Split Thickness Skin Grafting With and Without Surgical Removal of  Granulation  Tissue  in  Granulating  Wounds:  A  Single  Blinded,  Randomized Controlled Trial

Sharma, Samit; Pokhrel, Biraj; Rayamajhi, Sangam; Shrestha, Jayan M; Lohani, Ishwar

Publication:
Split Thickness Skin Grafting With and Without Surgical Removal of Granulation Tissue in Granulating Wounds: A Single Blinded, Randomized Controlled Trial

creativeworkseries.issn	ISSN (Print) : 1993-2979 \| ISSN (Online) : 1993-2987
dc.contributor.author	Sharma, Samit
dc.contributor.author	Pokhrel, Biraj
dc.contributor.author	Rayamajhi, Sangam
dc.contributor.author	Shrestha, Jayan M
dc.contributor.author	Lohani, Ishwar
dc.date.accessioned	2026-03-22T07:22:49Z
dc.date.available	2026-03-22T07:22:49Z
dc.date.issued	2021
dc.description	Samit Sharma1, Biraj Pokhrel2, Sangam Rayamajhi1, Jayan M Shrestha1, Ishwar Lohani1 1Department of Plastic Surgery and Burns, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal 2Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu, Nepal
dc.description.abstract	ABSTRACT Introduction: Split thickness skin graft (STSG) is a commonly carried out procedure in granulating wounds. The graft may be applied directly on the granulation tissue (without scrapping) or it may be applied after complete removal of the granulation tissue (after scrapping). Surgeons are divided on this issue. Methods: A single blinded, randomized, controlled trial was carried out between November 2017 and December 2018 in the Department of Plastic Surgery and Burns, Tribhuvan University Teaching Hospital, Kathmandu, Nepal. The study consisted of 62 patients who were divided into two groups. Group A consisted of patients undergoing removal of granulation tissue and Group B included patients on whom the skin graft was directly applied on the granulation tissue. On the 10th post-operative day, assessment of the graft take was done. Results: There was no statistically significant difference in graft take between group A and group B (p=0.59). The average drop in hemoglobin levels after the surgery was 1.6 gm% in group A and 0.4 gm% in group B and this difference was statistically significant. Also, the drop of serum protein after surgery was 8.6% gm/dl in group A and 1.0 gm/dl in group B and this difference was significant. Conclusion: There was no significant difference in the take of skin graft with or without removal of granulation tissue in our study. However, with lesser blood loss, lesser protein loss and lesser operative time, this study favours skin grafting without the removal of granulation tissue. Keywords: Graft take, granulation tissue, split thickness skin graft
dc.identifier.uri	https://hdl.handle.net/20.500.14572/5302
dc.language.iso	en_US
dc.publisher	Institute of Medicine
dc.subject	Graft take
dc.subject	granulation tissue
dc.subject	split thickness skin graft
dc.title	Split Thickness Skin Grafting With and Without Surgical Removal of Granulation Tissue in Granulating Wounds: A Single Blinded, Randomized Controlled Trial
dc.type	Article
dspace.entity.type	Publication
local.article.type	Original Article
oaire.citation.endPage	6
oaire.citation.startPage	1
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