Publication: Laryngeal Paraganglioma - A Rare Entity
Date
2023
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Laryngeal paragangliomas are neural crest derived rare neuroendocrine tumors
which originates from either superior or inferior laryngeal paraganglia. It arises
most commonly in supraglottis with mean age of 44 years and it is three times
more common in females.
This is a case of 39 years female who underwent endoscopic debulking and
excision of tumor for histopathological examination which proved to be poorly
differentiated squamous cell carcinoma and received a cycle of chemotherapy that
probably resulted in complete resolution of initial mass which was confirmed in
subsequent follow up. Futher immunohistochemistry examination diagnosed the
case as Laryngeal paraganglioma. With this consideration, how effective is the role
of chemotherapy in the management of proven case of Laryngeal paragangliomas?
KEY WORDS
Chemotherapy, Immunohistochemistry, Laryngeal paraganglioma
Description
Ghimire SB, KC AK, Karmacharya S, Shrestha BL
Department of Otorhinolaryngology-Head and Neck Surgery
Dhulikhel Hospital, Kathmandu University Hospital
Kathmandu University School of Medical Sciences
Dhulikhel, Kavre, Nepal
Keywords
Chemotherapy, Immunohistochemistry, Laryngeal paraganglioma