Publication: Study of Vitamin D Level in Paediatric Asthma at a Tertiary care Center
Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Introduction: There are few studies that suggest low Vitamin D levels are associated with asthma. Present study was conducted to evaluate the association between vitamin D levels with asthma and its severity in children.
Methods: This cross-sectional study included 70 children (35 asthmatic and 35 controls) aged between three to 12 yrs. CBC, AEC, IgE, spirometry, chest X-ray, and serum vitamin D levels were measured. Vitamin D levels were categorized according to guidelines of the American Academy of Paediatrics (2008) and compared between the two groups. The association between vitamin-D levels with asthma and its severity was studied.
Results: The mean age of study group cases was 9.23 ± 2.62 yr. The male:female ratio in the study group was 2.5: 1. Cough and wheezing was the commonest manifestation (100%). Most of the patients had mild asthma (45.71%). Asthma was more common in the urban population (68.57%) and children belonging to lower socioeconomic status (51.43%). The markers of allergic disorders {Eosinophils, AEC and IgE} were elevated (all p-values ≤ 0.0001) in study group. Mean serum vitamin D levels in the study group and control group patients were 45.21 ± 28.52 nmol/L and 57.03 ± 40.01 nmol / L respectively. The mean levels of vitamin D in the study group were insufficient as per AAP criteria. Vitamin D levels were more deficient in severe asthma (26.19 ± 14.46 nmol/L).
Description
Pankaj Kumar
Professor, Department of Paediatrics, S.N. Medical College, Agra, UP, India
Rajesh Kumar
Professor, Department of Paediatrics, S.N. Medical College, Agra, UP, India
Pratap Bhanu Singh
Junior Resident, Department of Paediatrics, S.N. Medical College, Agra, UP, India
Keywords
Allergy, Asthma, Vitamin D deficiency