Publication: The Glucose Challenge Test for Screening of Gestational Diabetes
Date
2011
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
The frequency of gestational diabetes mellitus (GDM) is 0.6% -15% of pregnant
woman. The modern trend towards the delay starting family is the main factor
responsible for increase prevalence of GDM. This condition is associated with
the adverse effect on mother and fetus, so it is important to find out the GDM by
screening of all the pregnant women.
Objective
To observe the feasibility of using the 50g GCT for all pregnant women attending
Dhulikhel Hospital, Obstetric OPD. To determine the incidence of gestational
diabetes in the population and to observe the maternal and fetal outcome among
those having an elevated GCT level and gestational diabetes.
Methods
A prospective and analytical study of 1598 pregnant women booked and delivered
between June 2009and August 2010. Glucose challenge test (GCT) performed by
using 50gm glucose and diagnosis of gestational diabetes performed by using the
Carpenter Coustan Criteria. Pregnancy outcomes were assessed by the gestation and
mode of delivery. Similarly, neonatal outcomes assessed in terms of birth weights,
APGAR scores, congenital abnormalities, hyperbilirubinaemia, hypoglycaemia or
respiratory distress syndrome.
Results
The detected incidence of gestational diabetes was 0.75%. With the threshold
plasma glucose level at140 mg/ dl, 198 women needed to undergo the 100g oral
glucose tolerance test and 12 women had gestational diabetes. The diagnostic yield
was 6.06%. Perinatal outcome was similar to the rest of the women with normal
glucose challenge test.
Conclusions
The 50g GCT is feasible and also helps to find out GDM. It is easy, user friendly,
cheap and convenient for screening purpose.
KEY WORDS
Glucose challenge test, gestational diabetes, oral glucose tolerance test
Description
Shrestha A, Chawla CD
Department of Obstetrics and Gynecology Dhulikhel Hospital - Kathmandu University Hospital Kavre, Nepal