Publication:
Scrub Typhus in Intensive Care Unit in Kathmandu – A case series from a tertiary center

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creativeworkseries.issnISSN 2822-1893 eISSN 2822-2016
dc.contributor.authorRajkarnikar, Ruja
dc.contributor.authorPaudyal, Bidhan Raj
dc.contributor.authorAwale, Ayushi
dc.contributor.authorShrestha, Sanjeev
dc.contributor.authorSharma, Lucky
dc.contributor.authorPant, Subash
dc.contributor.authorShrestha, Sanjeet K
dc.date.accessioned2026-02-03T08:08:16Z
dc.date.available2026-02-03T08:08:16Z
dc.date.issued2022
dc.descriptionRuja Rajkarnikar Department of Internal Medicine, Kathmandu Medical College Teaching Hospital, Nepal Bidhan Raj Paudyal Department of Internal Medicine, Kathmandu Medical College Teaching Hospital, Nepal Ayushi Awale Department of Internal Medicine, Kathmandu Medical College Teaching Hospital, Nepal Sanjeev Shrestha Department of Internal Medicine, Kathmandu Medical College Teaching Hospital, Nepal Lucky Sharma Department of Internal Medicine, Kathmandu Medical College Teaching Hospital, Nepal Subash Pant Department of Internal Medicine, Kathmandu Medical College Teaching Hospital, Nepal Sanjeet K Shrestha Department of Internal Medicine, Kathmandu Medical College Teaching Hospital, Nepal
dc.description.abstractAbstract: Scrub typhus is a rickettsial zoonosis caused by Orientia tsutsugamushi which can cause focal or disseminated vasculitis & perivasculitis in various body systems. It is endemic in many parts of Nepal & has been neglected & under-detected. We clinically assessed six patients from a intensive care unit in a tertiary hospital in Nepal that tested positive for scrub typhus using IgM ELISA & analyzed their profiles. Out of six patients, three were male & three were female with a mean age of 44.6 years. All six patients had chief complaints of fever & myalgia. Four patients presented with eschar. Three patients presented with septic shock while one presented with septicemia and meningoencephalitis. Only one patient had elevated white cell counts. Four out of six patients had transaminitis. Thrombocytopenia was present in two patients. Hypoalbuminemia was present in three patients. All cases tested negative for dengue, malaria, brucella, Leptospira, leishmania, salmonella & tuberculosis. This study points out the need for raising the index of suspicion & early screening of scrub typhus in patients with fever & laboratory findings of liver dysfunction or thrombocytopenia even with normal white cell counts.
dc.identifierhttps://doi.org/10.3126/nrj.v1i1.45300
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4487
dc.language.isoen_US
dc.publisherNepalese Respiratory Society
dc.subjectScrib typhus
dc.subjectZoonosis
dc.subjectTransaminitis
dc.subjectThrombocytopenia
dc.titleScrub Typhus in Intensive Care Unit in Kathmandu – A case series from a tertiary center
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Series
oaire.citation.endPage34
oaire.citation.startPage31
relation.isJournalIssueOfPublication08a1c199-f08d-4411-9c94-fab2af2925ad
relation.isJournalIssueOfPublication.latestForDiscovery08a1c199-f08d-4411-9c94-fab2af2925ad
relation.isJournalOfPublication91ea7cc8-46b2-4796-94bd-2998c28b5ebb

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