Publication: Anesthetic Management of a Case of Hemophagocytic Lymphohistiocytosis
| creativeworkseries.issn | ISSN (Print) : 1993-2979 | ISSN (Online) : 1993-2987 | |
| dc.contributor.author | Shrestha, Gentle S | |
| dc.contributor.author | Gulati, Harmeet | |
| dc.contributor.author | Acharya, Binita | |
| dc.contributor.author | Poudyal, Bishesh S | |
| dc.date.accessioned | 2026-04-03T07:16:26Z | |
| dc.date.available | 2026-04-03T07:16:26Z | |
| dc.date.issued | 2020 | |
| dc.description | Gentle S Shrestha1, Harmeet Gulati2, Binita Acharya1, Bishesh S Poudyal3 1Department of Anesthesiology, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Institute Of Medicine, Maharajgunj, Kathmandu, Nepal 2Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India 3Civil Service Hospital, Kathmandu, Nepal | |
| dc.description.abstract | ABSTRACT Hemophagocytic Lymphohistiocytosis (HLH) is characterized by an overwhelming activation of histiocytes and T lymphocytes leading to fulminant hemophagocytosis and organ damage. Anesthetic management of patients with HLH is associated with challenges such as pancytopenia, hemodynamic instability and infections. In addition to sepsis, metabolic acidosis, disseminated intravascular coagulation, multi-organ involvement with an exacerbation of symptoms with the use of anesthetic agents poses significant risk perioperatively. We present a case planned for excision of pilonidal sinus. The surgery was performed after thorough workup and with the patient in remission. Elective procedures should ideally be performed with patients in remission. Cases receiving concurrent therapy with immunomodulators and steroids require special attention due to possible interaction with anesthetic agents and the need for perioperative steroid supplementation. Keywords: Anesthetic management, hemophagocytic lymphohystiocytosis, pancytopenia, steroids | |
| dc.identifier | https://doi.org/10.59779/jiomnepal.1087 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/5598 | |
| dc.language.iso | en_US | |
| dc.publisher | Institute of Medicine | |
| dc.subject | Anesthetic management | |
| dc.subject | hemophagocytic lymphohystiocytosis | |
| dc.subject | pancytopenia | |
| dc.subject | steroids | |
| dc.title | Anesthetic Management of a Case of Hemophagocytic Lymphohistiocytosis | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Case Report | |
| oaire.citation.endPage | 61 | |
| oaire.citation.startPage | 59 | |
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