Publication:
Histopathological study of solitary nodules of thyroid

creativeworkseries.issn1812-2027
dc.contributor.authorKhadilkar, UN
dc.contributor.authorMaji, P
dc.date.accessioned2025-08-03T06:48:07Z
dc.date.available2025-08-03T06:48:07Z
dc.date.issued2008
dc.descriptionKhadilkar UN 1 , Maji P2 1 Professor of Pathology, Kasturba Medical College, Mangalore, 2 Consultant Pathologist, Ramkrishna Road, Ranisagar [North], P.O.Dt. Burdwan, West Bengal
dc.description.abstractAbstract Objective: To determine the incidence of various thyroid disorders manifesting as Solitary Thyroid Nodule and also to evaluate the histomorphology of the lesions. Materials and methods: Hundred specimens of Solitary Thyroid Nodules were studied for gross characteristics, microscopic features, age and sex incidence. Results: Of the 100 cases of Solitary Thyroid Nodules, 66% were non neoplastic and 34% were neoplastic. Among the neoplasms, 21% were malignant and 13% were benign. The age incidence ranged from 20-50 years for non neoplastic lesions and 20-40 years for neoplasms. A female preponderance was seen for both non neoplastic and neoplastic conditions. The solitary nodules involved the right side of the thyroid more commonly than the left. Involutional colloid nodule was the predominant type of solitary nodule (52%). Among the malignant neoplasms, papillary carcinoma was the commonest solitary nodule (13%). One case each of hyalinising trabecular adenoma, columnar cell variant of papillary carcinoma and medullary carcinoma unusually presenting as solitary nodules were encountered in the present study. Conclusion: Histomorphologic evaluation of Solitary Thyroid Nodules presenting without a background setting of multinodular goiter is challenging and mandatory as the diagnoses ranges from the common non neoplastic lesions like involuting nodules to the rare neoplastic conditions like medullary carcinoma. Key words: Solitary Thyroid Nodule morphology, involuting nodule, medullary carcinoma
dc.identifier.urihttps://hdl.handle.net/20.500.14572/1157
dc.language.isoen_US
dc.publisherKathmandu University
dc.titleHistopathological study of solitary nodules of thyroid
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage490
oaire.citation.startPage486
relation.isJournalIssueOfPublication1fc39eac-2b30-4ac7-95e8-7bf6cb71abb9
relation.isJournalIssueOfPublication.latestForDiscovery1fc39eac-2b30-4ac7-95e8-7bf6cb71abb9
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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