Publication: Prevalence Survey of Antimicrobial Use among Admitted Patients in Tertiary Care hospital: An observational study
Files
Date
2025
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Monitoring the antimicrobial use is one of the key strategies to address the growing
global threat of antimicrobial resistance.
Objective
To find out antimicrobial usage at tertiary care hospital of Lalitpur, Nepal.
Result
An observational cross-sectional study was carried out at the Patan Academy of Health
Sciences, Lalitpur, Nepal on September 25 and 26, 2023. World Health Organization
point prevalence survey methodology was used with minor modification to meet
hospital’s context. The data on antimicrobial usage were collected from the medical
records of patients admitted at or before 08:00 am on the day of the study in the
acute care ward.
Result
The study involved 324 inpatients, with females comprising 176 (54.3%) and males
148(45.7%). The mean age was 37.89 years ± 24.87. Antibiotics usage was 78.1%.
A total of 471 drug was prescribed of which 312 (66.2%) was used for therapeutic
purpose and 159 (33.8%) for prophylaxis. Of 312 antibiotics, 283 (90.7%) were
utilized empirically. Majority of prescribed medications belonged to watch group 16
(48.5%). Ceftriaxone was the most frequently prescribed antibiotic 142 (30.1%) and
was the preferred choice for surgical prophylaxis 68 (94.4%). A total of 24 (72.7%)
drugs were prescribed from the National List of Essential Medicines and 432 (91.7%)
prescriptions were written using generic names.
Conclusion
The use of antibiotic was high, with good adherence to essential medicines and
generic prescribing. Strengthening antimicrobial stewardship and evidence-based
practices can further optimize prescribing, enhance patient safety and help combat
antimicrobial resistance effectively.
KEY WORDS
Antibiotic, Nepal, Point prevalence survey, Tertiary care hospital
Description
Aryal S,1 Joshi M,1 Uprety BN,1 Shrestha RK,1 Gupta M,1 Shah P,1 Rajbhandari P,2 Amatya R,3 Shrestha P,3 Ojha AR4
1Department of Pharmacology
Patan Academy of Health Sciences
Lagankhel, Lalitpur, Nepal
2Department of Microbiology
Patan Academy of Health Sciences
Lagankhel, Lalitpur, Nepal
3FHI 360 Nepal
Anamika Galli, Baluwatar
Kathmandu, Bagmati, Nepal
4Department of Pediatric
Patan Academy of Health Sciences
Lagankhel, Lalitpur, Nepal
Keywords
Antibiotic, Nepal, Point prevalence survey, Tertiary care hospital