Article:
Drug induced rowell’s syndrome: a rare presentation

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creativeworkseries.issnOnline ISSN: 2676-1424; Print ISSN: 2676-1319
dc.contributor.authorRana, Arnija
dc.contributor.authorThapa, Deeptara Pathak
dc.contributor.authorShrestha, Shristi
dc.contributor.authorAdhikari, Prabin
dc.contributor.authorShrestha, Asim
dc.creator.affiliationDepartment of Dermatology, Nepal Medical College Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Dermatology, Nepal Medical College Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Dermatology, Nepal Medical College Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Internal Medicine, Nepal Medical College Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationNepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.date.accessioned2026-10-29T05:08:34Z
dc.date.available2026-10-29T05:08:34Z
dc.date.issued2024
dc.description.abstractAbstract: Rowell’s syndrome (RS) is a rare disorder characterized by Erythema multiforme (EM)-like lesions in a patient with lupus erythematosus, either systemic lupus erythematosus (SLE) or cutaneous lupus erythematosus (CLE). A 35 years old female presented in our dermatology outpatient department (OPD) with complaint of hemorrhagic crusting of lips and multiple discrete targetoid lesions over the chest, upper limb, and gluteal region. Investigations revealed a speckled pattern of antinuclear antibody (ANA), anti-Smith antibody, anti-ds DNA antibody, and strongly positive anti-Ro antibody. According to the clinical evaluation and investigations, the diagnosis of drug induced RS was made. The likely role of proton pump inhibitors, namely esomeprazole as a triggering factor is discussed. After stopping esomeprazole and starting medications with oral steroids and hydroxychloroquine, her good response to treatment was noted.
dc.identifier.doihttps://doi.org/10.3126/nmcj.v26i1.63893
dc.identifier.urihttps://hdl.handle.net/20.500.14572/8203
dc.language.isoen_US
dc.publisherNepal Medical College Pvt. Ltd.
dc.subjectErythema multiforme
dc.subjectSystemic lupus erythematosus
dc.subjectRowell syndrome
dc.titleDrug induced rowell’s syndrome: a rare presentation
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage82
oaire.citation.startPage79
relation.isJournalIssueOfPublicationad330a3e-75f1-4484-8269-5d082cde50f7
relation.isJournalIssueOfPublication.latestForDiscoveryad330a3e-75f1-4484-8269-5d082cde50f7
relation.isJournalOfPublication865934c8-5e95-468c-8ca6-7bb2529e4064

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