Publication:
Modified Sick Neonatal Score (MSNS) in Predicting the Outcome of Neonates in Tertiary Care Hospital

creativeworkseries.issnISSN 1990-7974 eISSN 1990-7982
dc.contributor.authorTwanbasu, Sajal
dc.contributor.authorAmatya, Puja
dc.contributor.authorShah, Ganesh
dc.date.accessioned2025-10-30T09:58:54Z
dc.date.available2025-10-30T09:58:54Z
dc.date.issued2023
dc.descriptionSajal Twanbasu Resident, Patan Academy of Health Sciences, Lalitpur, Nepal. Puja Amatya Assistant Professor, Department of Paediatrics, Patan Academy of Health Sciences, Lalitpur, Nepal. Ganesh Shah Professor and Head of Department, Patan Academy of Health Sciences, Lalitpur, Nepal.
dc.description.abstractAbstract: Introduction: Neonatal disease severity scoring systems are widely used to predict severity of illness. Existing scoring systems contain variables like pH, PO2 / FiO2 ratio, and base excess, which are difficult to obtain in resource-limited settings. Modified sick neonatal score (MSNS) is based on eight clinical variables which are easy to calculate and are also accurate enough at the same time. This study was done to evaluate MSNS for predicting the outcome of neonates in our settings. Methods: This was prospective observational study done at neonatal intensive care unit (NICU) of tertiary care hospital in Nepal from February 2021 to January 2022. The parameters required for the score were recorded at admission. Total score was calculated and outcome was noted. Data collected was analyzed using SPSS Statistics for Windows, v21.0. Chi square test, Mann-Whitney U test and ROC analysis were used for statistical analysis. Results: Total of 195 neonates were discharged and 37 expired. The mean MSNS score among expired was 8.16 ± 1.625 and discharged was 10.99 ± 1.753. For a cutoff score of ≤ 10, sensitivity and specificity; Positive and negative predictive value were 89.2% and 60.5%; 30.7% and 98.3% respectively. The area under the curve (AUC) of MSNS was 0.875 (CI 95%; 0.817 - 0.934). Lower MSNS score was also associated with requirement of iontrope and ventilator support. Conclusions: MSNS can be used as an important clinical tool for predicting the severity of disease in neonates in resource limited settings.
dc.identifierhttps://doi.org/10.60086/jnps490
dc.identifier.urihttps://hdl.handle.net/20.500.14572/2934
dc.language.isoen_US
dc.publisherNepal Paediatric Society (JNPS)
dc.subjectMortality
dc.subjectMSNS
dc.subjectNeonate
dc.subjectNepal
dc.subjectScoring system
dc.titleModified Sick Neonatal Score (MSNS) in Predicting the Outcome of Neonates in Tertiary Care Hospital
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage65
oaire.citation.startPage60
relation.isJournalIssueOfPublication4219d666-b677-4efe-b1ea-eed73bb7fb76
relation.isJournalIssueOfPublication.latestForDiscovery4219d666-b677-4efe-b1ea-eed73bb7fb76
relation.isJournalOfPublication6f9be05c-05a9-4a3e-a5b5-a19a15ab042c

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