Publication: Relapsing Parvovirus B19 Infection after Intravenous Immunoglobulin in Renal Transplant Recipient: A Case Report
Date
2023
Journal Title
Journal ISSN
Volume Title
Publisher
Institute of Medicine
Abstract
ABSTRACT
Parvovirus B19 has special affinity to erythroid progenitor cells leading to destruction and inhibition of erythropoiesis. One of its presentations is pure red cell aplasia in patients receiving immunosuppressive medications after organ transplantation. Intravenous immunoglobulin (IVIG) and reduction of immunosuppressive medication has been used for treatment but the effects of IVIG may be temporary. Here we present a case of Relapsing infection due to Parvovirus B19 after IVIG in a renal transplant recipient in Nepal. This case shows that in renal transplant patients presenting with anemia and low reticulocyte count, Parvovirus B19 infection should be suspected. Treatment with IVIG has good results but there may be relapse of infection.
KeywordsParvovirus B19; intravenous immunoglobulin; renal transplant; relapse;
Description
Rabin Nepali1, Pawan R Chalise2, Dibya Singh Shah1
1Department of Nephrology, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal
2Department of Urology and Kidney Transplant Surgery, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal
Keywords
Parvovirus B19, intravenous immunoglobulin, renal transplant, relapse