Article: Hormonal changes in intracranial hemorrhage
| creativeworkseries.issn | JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X | |
| dc.contributor.author | Shrestha, Rajendra | |
| dc.contributor.author | Pradhan, Reeka | |
| dc.contributor.author | Pradhan, Mahesh | |
| dc.contributor.author | You, Chao | |
| dc.creator.affiliation | Department of Neurosurgery,NAMS, Bir Hospital/ National Trauma Centre. | |
| dc.creator.affiliation | Paropkar maternity and women’s Hospital, Thapathali, Nepal. | |
| dc.creator.affiliation | Department of Surgery, Sumeru Hospital, Nepal. | |
| dc.creator.affiliation | Department of Neurosurgery, West China Hospital, Sichuan University, China. | |
| dc.date.accessioned | 2026-09-22T06:32:21Z | |
| dc.date.available | 2026-09-22T06:32:21Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | Abstract Introduction: The purpose of this study was to investigate the changes of serum ACTH and Thyroid hormone level in the acute phase of ICH. Methods: Sixty patients with spontaneous ICH were assessed regarding hormonal changes by measuring ACTH and Thyroid hormone level. The relationships of hormone concentrations to clinical and radiological parameters were evaluated at hospital admission (t0), 5 days (t1) and 10 days (t2). The results were statistically analyzed. Results: ACTH, TSH, Thyroxine, and free Thyroxine were not signiï¬cantly different among the three time periods (P > 0.05), while Triiodothyronine (T3) and free Triiodothyronine (FT3) were signiï¬cantly different (P < 0.05). T3 and FT3 were not signiï¬cantly different among patients with hemorrhage of different locations (P>0.05). There were significant negative correlations between T3 and FT3 with volume of ICH (r=-0.63 and r=-0.25) and there were positive correlations between T3 and FT3 with GCS (r=0.63 and r=0.37) respectively on admission day (p <0.05). Conclusions: Hormonal secretion patterns is associated with the severity of ICH. This is an important index to evaluate the disease severity and prognosis. Keywords: ACTH; ICH; lymphocyte ICH; Thyroid hormone. | |
| dc.identifier.doi | https://doi.org/10.31729/jnma.3026 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/7804 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Medical Association | |
| dc.subject | ACTH | |
| dc.subject | ICH | |
| dc.subject | lymphocyte ICH | |
| dc.subject | Thyroid hormone | |
| dc.title | Hormonal changes in intracranial hemorrhage | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 167 | |
| oaire.citation.startPage | 163 | |
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