Publication: Association of Cardiovascular Risk Factors and Coronary Artery Lesion Among Coronary Artery Disease Patients
Date
2014
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Coronary artery disease (CAD) is associated with the numbers of risk factors causing
coronary atherosclerosis. Coronary artery stenosis is mostly caused by coronary
atherosclerosis.
Objective
This study aims to analyze the association between coronary artery stenosis and
cardiovascular risk factors.
Methods
An observational study was conducted among CAD patients. The diagnostic coronary
angiogram was performed from femoral approach using standard catheters and
techniques to find out any abnormalities.
Result
A total 73 patients (44 male and 29 female) with coronary artery disease undergoing
diagnostic coronary angiography was included with the documented cardiovascular
risk factors. The coronary stenosis was found in 40 patients on the basis of stenosis
grading. Among the established cardiovascular risk factors, sex, diabetes mellitus
and smokers show are significantly associated with coronary stenosis among CAD
patients. The present study shows the significant association of coronary stenosis
among male CAD patients (OR 2.47; CI 0.94 – 6.48, p <0.05) and similar association
has been observed in diabetes mellitus (OR 3.32; CI 1.12 – 9.84, p <0.05) and
smoking (OR 4.10; CI 1.45 – 11.61, p <0.01).
Conclusion
The prevalence of CAD is increased with numbers of presence of cardiovascular risk
factors. Male gender, diabetes mellitus and smoking are significantly associated with
coronary stenosis among CAD patients. However, hypertension and dyslipidemia
are comparable between coronary stenosis and no significant stenosis group.
KEY WORDS
Acute coronary syndrome, coronary angiography, coronary artery disease, stable
angina
Description
Koju R,1 Humagain S,1 Khanal K2
1Department of Internal Medicine
Dhulikhel Hospital, Kathmandu University Hospital
Dhulikhel, Kavre, Nepal
2Department of Community Medicine
Kathmandu University School of Medical Sciences
Dhulikhel, Kavre, Nepal