Article:
Swyer syndrome : a case report with literature review

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creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorPatnayak, R
dc.contributor.authorSuresh, V
dc.contributor.authorJena, A
dc.contributor.authorRajagopal, G
dc.contributor.authorVijayalakshmi, B
dc.contributor.authorReddy, AP
dc.contributor.authorRukumangadha, M
dc.contributor.authorSachan, A
dc.creator.affiliationDepartment of Pathology, Sri Venkateswar Institute Of Medical Sciences, Tirupati, India.
dc.creator.affiliationDepartment of Endocrinology, Sri Venkateswar Institute Of Medical Sciences, Tirupati, India.
dc.creator.affiliationDepartmentof Surgical Oncology, Sri Venkateswar Institute Of Medical Sciences, Tirupati, India.
dc.creator.affiliationDepartmentof Radiology, Sri Venkateswar Institute Of Medical Sciences, Tirupati, India.
dc.creator.affiliationDepartmentof Radiology, Sri Venkateswar Institute Of Medical Sciences, Tirupati, India.
dc.creator.affiliationDepartmentof Radiology, Sri Venkateswar Institute Of Medical Sciences, Tirupati, India.
dc.creator.affiliationDepartment of Pathology, Sri Venkateswar Institute Of Medical Sciences, Tirupati, India.
dc.creator.affiliationDepartment of Endocrinology, Sri Venkateswar Institute Of Medical Sciences, Tirupati, India.
dc.date.accessioned2026-11-04T06:15:59Z
dc.date.available2026-11-04T06:15:59Z
dc.date.issued2012
dc.description.abstractAbstract Gonadoblastomas are known to develop in dysgenetic gonads, especially so, if Y chromosome material is present. A 20-years- old girl who noticed breast development since the age of 12 years presented with primary amenorhoea, distension of lower abdomen and intermittent pain for two months. She had breakthrough bleeding with six months of estrogen replacement. Tanner breast stage was fi ve and pubic hair stage was also fi ve. Examination revealed a mass in the lower abdomen extending into hypogastrium, umbilical and lumbar regions. Her gonadotropin levels were grossly elevated. Karyotyping showed 46XY. CT scan of abdomen showed a 17X11 cm mass in the pelvis without visible gonads. Surgical excision of the mass along with bilateral salpingophorectomy was performed. Histopathology revealed the mass to be a dysgerminoma, while the right gonad lodged gonadoblastoma. She was diagnosed as a rare case of Swyer syndrome. Keywords: Dysgerminoma, Gonadoblastoma, Swyer syndrome, XY gonadal dysgenesis
dc.identifier.doihttps://doi.org/10.31729/jnma.72
dc.identifier.urihttps://hdl.handle.net/20.500.14572/8317
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectDysgerminoma
dc.subjectGonadoblastoma
dc.subjectSwyer syndrome
dc.subjectXY gonadal dysgenesis
dc.titleSwyer syndrome : a case report with literature review
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage74
oaire.citation.startPage72
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relation.isJournalIssueOfPublication.latestForDiscovery9cdc19a1-d667-4f9f-916c-4eb73fb77fa1
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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