Study of Serum Magnesium Levels in Patients Admitted with Sepsis in Intensive Care Unit

Patil, PSG; Aslam, SS

Publication:
Study of Serum Magnesium Levels in Patients Admitted with Sepsis in Intensive Care Unit

creativeworkseries.issn	1812-2027
dc.contributor.author	Patil, PSG
dc.contributor.author	Aslam, SS
dc.date.accessioned	2026-01-04T06:45:54Z
dc.date.available	2026-01-04T06:45:54Z
dc.date.issued	2023
dc.description	Patil PSG, Aslam SS Department of General Medicine MS Ramaiah Medical College Bengaluru, India
dc.description.abstract	ABSTRACT Background Magnesium plays an important role in sepsis, and this could be attributed to its effects on the immune system, which are important in the pathogenesis of sepsis. Magnesium deficiency, one of the underrated electrolyte abnormalities, is observed in critically ill patients admitted to intensive care unit (ICU). Objective To find the association of serum magnesium with the outcome, duration, and need for ventilation. Method The hospital-based prospective observational study included patients > 18 years (N=150) with sepsis admitted to intensive care unit. Patients were divided into normomagnesemia (n=75) and hypomagnesemia (n=75) groups. Sequential Organ Failure Assessment Score (SOFA) score, length of intensive care unit stay, need and duration of mechanical ventilatory requirement, and outcomes were compared between the two groups. Result The mean Sequential Organ Failure Assessment score (5.87 ± 2.31 vs. 3.85 ± 1.75), mean duration of intensive care unit stay (in days) (7.21 ± 1.74 vs. 5.24 ± 1.38), the mean duration of mechanical ventilatory requirement (in days) (4.05 ± 3.47 vs. 1.13 ± 1.98), and mortality rate were (33% vs. 4%) were higher in the hypomagnesemia group when compared to the normomagnesemia group (p < 0.001 for all). Conclusion The study concludes that hypomagnesaemia is a significant electrolyte abnormality in critically ill sepsis patients. Hypomagnesaemia, Sequential Organ Failure Assessment Score, and mechanical ventilation are the factors that independently predicted mortality in intensive care unit patients. Hence, clinicians should regularly monitor the occurrence of hypomagnesemia in intensive care unit patients to reduce its poor clinical outcomes. KEY WORDS Artificial, Critical care, Magnesium, Mortality, Organ dysfunction scores, Respiration, Sepsis
dc.identifier.uri	https://hdl.handle.net/20.500.14572/4013
dc.language.iso	en_US
dc.publisher	Kathmandu University
dc.subject	Artificial
dc.subject	Critical care
dc.subject	Magnesium
dc.subject	Mortality
dc.subject	Organ dysfunction scores
dc.subject	Respiration
dc.subject	Sepsis
dc.title	Study of Serum Magnesium Levels in Patients Admitted with Sepsis in Intensive Care Unit
dc.type	Article
dspace.entity.type	Publication
local.article.type	Original Article
oaire.citation.endPage	27
oaire.citation.startPage	23
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