Publication: Eosinophilic Granuloma of Mandible: A Diagnostic Challenge
Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Eosinophilic Granuloma is the mildest and localized form of Langerhans Cell
Histiocytosis and is characterized by clonal proliferation of Langerhans cells.
It is a rare disease, accounting for less than 1% of all the osseous neoplasms. It
has predilection for the axial skeleton and incidence in jaws is just 7.9%. It lacks
pathognomonic clinical and radiographic trait and hence is difficult to make a correct
diagnosis without histopathological and immunohistochemical examination. This
report describes a case of Eosinophilic Granuloma of mandible in 30 years old male
who presented with complain of unhealed extraction wound and was clinically
diagnosed as chronic suppurative osteomyelitis. The final diagnosis of Eosinophilic
Granuloma was made only after histopathological and immunohistochemical
evaluations.
KEY WORDS
Eosinophilic granuloma, Immunohistochemistry, Langerhans cell histiocytosis
Description
Bajracharya B,1 Poudel P,1 Bajracharya D,1 Bhattacharyya S,1 Shakya P2
1Department of Oral Pathology
Kantipur Dental College, Basundhara, Kathmandu, Nepal.
2Department of Oral Surgery
Peoples Dental College,
Shorakhutte, Kathmandu, Nepal
Keywords
Eosinophilic granuloma, Immunohistochemistry, Langerhans cell histiocytosis