Browsing by Author "Pandey, S"
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Publication Evaluation of Lipid Peroxidation and Antioxidants’ Status in Metabolic Syndrome(Kathmandu University, 2010) Shrestha, S; Chandra, L; Aryal, M; Das, BKL; Pandey, S; Baral, NABSTRACT Background Metabolic syndrome is a constellation of physical conditions and metabolic abnormalities, commonly occurring together, that increases an individual’s risk for development of type 2 diabetes mellitus and cardiovascular diseases. Oxidative stress is associated with diabetes, hypertension and other cardiovascular diseases while the role of oxidative stress in pathogenesis of MS is not clearly defined. Objectives The study aims to find out the prevalence of metabolic syndrome in faculty and staff members at BP Koirala Institute of Health Sciences, Dharan, Nepal and to evaluate oxidative stress levels in subjects with metabolic syndrome. Methods 118 healthy participants working at B. P. Koirala Institute of Health Sciences, Dharan, Nepal were selected at random for this cross-sectional study and blood samples were collected for the estimation of the following biochemical analytes; fasting glucose; triglycerides; total cholesterol; high density lipoprotein cholesterol; Albumin; uric acid; Bilirubin; Malondialdehyde; Catalase; Glutathione peroxidase; Superoxide Dismutase; Glutathione; vitamin C; and lastly vitamin E. Results In this cross-sectional study, 39% subjects were diagnosed with metabolic syndrome , particularly in sedentary subjects. There was no difference in oxidative stress except significant rises in serum uric acid levels and catalase activity in subjects diagnosed with metabolic syndrome . Conclusion The prevalence of metabolic syndrome is higher without oxidative stress in this study, which suggests that oxidative stress does not contribute to the pathogenesis of MS in otherwise healthy subjects. Key Words antioxidants, lipid peroxidation, metabolic syndrome, oxidative stressPublication Health profile of school children in Bhaktapur(Kathmandu University, 2005) Pandey, S; Dudani, I; Pradhan, AObjectives: To find out the existing common health problems among school children and to arouse health consciousness among the children. Material and methods: All the students studying in Mandev Amrit Smriti School, Jhaukhel VDC of Bhaktapur District were included in the sample. The methods used were the interview, clinical history and check-up for provisional diagnosis. A semi-structured questionnaire was used to record information regarding name, age, sex, standard in which s/he was studying, physical examination/ personal hygiene, anthropometric measurements, clinical findings, provisional diagnosis etc. The medical instruments used in the survey were: weighing machine, measuring tape, and thermometer. Common medicines like Jeevanjal packets, Albendazole tablets for deworming, Metron, amoxicyllin, paracetamol, Tagyl etc were also distributed to the needy students. Results and Conclusion: The physical examination of all 118 students in age group ranging from 3 to 13 years of Mandev Amrit Smriti School situated at Jhaukhel VDc of Bhaktapur district was carried out. Thirteen health related problems were detected in this study. The most important three problems were ear problems (22.03%), worm infestation (16.10%) and dental caries (13.56%). Thus school health education should mainly aim at these problems and the care and cleanliness of ears and teeth by proper and regular brushing should be stressed. Applying Water low classification, 33% males were found normal as per their weight for age. 61.9% males were stunted and 4.8 % males were wasted. Likewise, 54.6% females were found normal as per their weight for age. 43.6% females were stunted and 1.8 % females were wasted. Key Word: School health, Health problemsPublication Leflunomide Induced DRESS Syndrome: A Case Report(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2012) Parajuli, S; Chaudhary, D; Pandey, S; Baral, S; Pokhrel, D BNA Keywords: Leflunomide, Dress syndromePublication Pachydermoperiostosis ('Touraine-Solente-Gole' Syndrome)(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2013) Sharma, R; Pandey, S; Choudhary, D; Pokhrel, DBNo Abstract Keywords: Pachydermia, primary hypertrophic osteoarthropathy, clubbing