Publication: Sepsis among Patients Admitted to the Intensive Care Unit of a Tertiary Care Centre
Date
2023
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Introduction: Sepsis is a life-threatening dysfunction and is one of the common causes of admission in intensive care units. Early diagnosis and management improves the outcome of patients. The aim of this study was to find out the prevalence of sepsis among patients admitted to the intensive care unit of a tertiary care centre.
Methods: A descriptive cross-sectional study was conducted among patients admitted to the intensive care unit of a tertiary care centre after obtaining ethical approval from the Institutional Review Committee. Data of patients admitted from 1 February 2022 to 31 January 2023 was collected between 6 April 2023 to 27 April 2023. Convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.
Results: Among 1001 patients, the prevalence of sepsis was 278 (27.77%) (25-30.54, 95% Confidence Interval). Among them, 209 (75.17%) developed septic shock. The mean age was 56.6±19.34 years. Pneumonia 43 (15.46%) and genitourinary infection 43 (15.46%) were the most common sources of infection and the source was unknown in 124 (44.60%) of patients. Hypertension 75 (26.97%) was the most common comorbidity. Acute kidney injury 166 (59.71%) was the most common complication followed by thrombocytopenia 165 (59.35%) and transaminitis 79 (28.41%).
Conclusions: The prevalence of sepsis among patients admitted to the intensive care unit was higher than other studies done in similar settings.
Description
Laxman Mandal
Department of Internal Medicine, Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal
Garima Rijal
Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal
Raj Singh
Buddha Minimal Access Intervention Centre, Teku, Kathmandu, Nepal
Bhawana Tiwari
Himal Hospital, Gyaneshwor, Kathmandu, Nepal
Farhat Jahan
Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal
Dipti Lama
Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal
Sagun Shrestha
Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal
Ram Narayan Kurmi
Maharajgunj Primary Health Centre, Maharajgunj, Kapilvastu, Nepal
Uma Das
Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal