Publication: Macrophage Activation Syndrome secondary to Systemic Juvenile Idiopathic Arthritis: A Case Report
Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract:
Macrophage activation syndrome is a rare but a life threatening condition commonly associated with Systemic Juvenile Idiopathic Arthritis. Its clinical presentation includes fever, hepatosplenomegaly, hypertriglyceridemia, hypofibrinogenemia, hyperferritinemia and impaired liver enzymes. The symptoms are alarming yet non-specific and often lead to a delayed diagnosis. A 12 year male presented with a history of intermittent fever and was started on antibiotics but failed to respond after several days of hospital stay. After a series of investigations to rule out multiple diagnoses he was diagnosed as a case of Macrophage Activation Syndrome secondary to Systemic onset Juvenile Arthritis and was treated with steroids.
Description
Rishikesh Kafle
Department of Pediatrics, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal
Anwesh Bhatta
Department of Pediatrics, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal
https://orcid.org/0000-0002-6100-545X
Sumit Gami
Patan Academy of Health Sciences, Lalitpur, Nepal.
https://orcid.org/0000-0002-1449-7105
Abhin Sapkota
Vayodha Hospitals Private Limited, Balkhu, Kathmandu, Nepal
https://orcid.org/0000-0002-4146-7016
Dipesh Sharma
Karuna Hospital, Budanilkantha, Kathmandu, Nepal
https://orcid.org/0000-0002-9032-2219
Arabindra Yadav
Department of Pediatrics, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal
https://orcid.org/0000-0003-4301-7200
Vijaya Kumar Chikanbanjar
Department of Pediatrics, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal
https://orcid.org/0000-0001-9062-0083
Keywords
uvenile arthritis, macrophage activation syndrome, steroids.