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Macrophage Activation Syndrome secondary to Systemic Juvenile Idiopathic Arthritis: A Case Report

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creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorKafle, Rishikesh
dc.contributor.authorBhatta, Anwesh
dc.contributor.authorGami, Sumit
dc.contributor.authorSapkota, Abhin
dc.contributor.authorSharma, Dipesh
dc.contributor.authorYadav, Arabindra
dc.contributor.authorChikanbanjar, Vijaya Kumar
dc.date.accessioned2026-02-13T05:03:44Z
dc.date.available2026-02-13T05:03:44Z
dc.date.issued2021
dc.descriptionRishikesh Kafle Department of Pediatrics, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal Anwesh Bhatta Department of Pediatrics, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal https://orcid.org/0000-0002-6100-545X Sumit Gami Patan Academy of Health Sciences, Lalitpur, Nepal. https://orcid.org/0000-0002-1449-7105 Abhin Sapkota Vayodha Hospitals Private Limited, Balkhu, Kathmandu, Nepal https://orcid.org/0000-0002-4146-7016 Dipesh Sharma Karuna Hospital, Budanilkantha, Kathmandu, Nepal https://orcid.org/0000-0002-9032-2219 Arabindra Yadav Department of Pediatrics, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal https://orcid.org/0000-0003-4301-7200 Vijaya Kumar Chikanbanjar Department of Pediatrics, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal https://orcid.org/0000-0001-9062-0083
dc.description.abstractAbstract: Macrophage activation syndrome is a rare but a life threatening condition commonly associated with Systemic Juvenile Idiopathic Arthritis. Its clinical presentation includes fever, hepatosplenomegaly, hypertriglyceridemia, hypofibrinogenemia, hyperferritinemia and impaired liver enzymes. The symptoms are alarming yet non-specific and often lead to a delayed diagnosis. A 12 year male presented with a history of intermittent fever and was started on antibiotics but failed to respond after several days of hospital stay. After a series of investigations to rule out multiple diagnoses he was diagnosed as a case of Macrophage Activation Syndrome secondary to Systemic onset Juvenile Arthritis and was treated with steroids.
dc.identifierhttps://doi.org/10.31729/jnma.7019
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4735
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectuvenile arthritis
dc.subjectmacrophage activation syndrome
dc.subjectsteroids.
dc.titleMacrophage Activation Syndrome secondary to Systemic Juvenile Idiopathic Arthritis: A Case Report
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage1169
oaire.citation.startPage1166
relation.isJournalIssueOfPublication845ac967-f06a-4939-8311-7a30cb7c0f0a
relation.isJournalIssueOfPublication.latestForDiscovery845ac967-f06a-4939-8311-7a30cb7c0f0a
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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