Publication: Anuria, an Atypical Presentation of Leptospirosis: A Case Report
Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract:
Leptospirosis, an underreported disease, is a highly prevalent spirochaetal zoonotic disease in both tropical and temperate climates. Symptoms can range from mild illness to potentially life-threatening infection. Laboratory tests are nonspecific. Microbiological confirmation is not widely available in endemic developing countries like Nepal. We need to rely on the serologic test, which has its own pitfalls in the initial days of illness. Here, we report a case of 56 years old female from the western region of Nepal who presented with fever, jaundice and anuria. She initially tested negative for leptospirosis but was later found to be positive in the second week of illness. Unlike the usual non-oliguric renal failure in leptospirosis, she presented with anuria requiring haemodialysis and subsequently had a good recovery with treatment. We highlight the importance of clinical suspicion and logical interpretation of serologic tests based on its timing from the onset of illness.
Description
Shambhu Khanal
Department of Internal Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal
https://orcid.org/0000-0002-1247-7389
Biraj Pokhrel
Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu, Nepal
https://orcid.org/0000-0003-2059-5876
Madalasha Pokhrel
Department of Internal Medicine, Manipal College of Medical Sciences, Pokhara, Nepal
https://orcid.org/0000-0002-5770-6958
Rukshar Thapa
Department of Internal Medicine, Manipal College of Medical Sciences, Pokhara, Nepal
Rabin Nepali
Department of Nephrology, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal
https://orcid.org/0000-0002-5663-7890
Keywords
anuria, case report, leptospirosis, renal insufficiency, zoonoses.