Publication: Kawasaki Disease- Management Strategies Given Symptoms Overlap to COVID-19: A Review
Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract:
Kawasaki disease is an acute, self-limiting vasculitis in children. Early treatment is necessary to prevent cardiovascular complications. The acute phase of Kawasaki disease may present with hemodynamic instability. An association between viral respiratory infections and Kawasaki disease has been reported. Studies have shown that Kawasaki and Kawasaki-like disease may be associated with and have symptoms overlapping COVID-19. Children with COVID-19 may present as Kawasaki-like disease with pediatric inflammatory multisystem syndrome, or macrophage activation syndrome. Clinicians need to be aware of the early diagnosis and management of Kawasaki disease to prevent the development of coronary artery aneurysms. The symptoms overlap of multisystem inflammatory disease seen in COVID-19 adds to the difficulties in timely diagnosis and treatment. Children with Kawasaki disease require regular follow-up plans for coronary artery aneurysms. This adds to the difficulties during the changed environment of COVID-19 for control and prevention. Missed diagnosis and early treatment of Kawasaki disease with immunoglobulin and aspirin results in the development of coronary artery aneurysm in up to 25% of cases, with grave consequences. Here, we briefly review the management of typical and atypical Kawasaki disease which has symptoms overlapping with the multisystem inflammatory disease as seen in COVID-19.
Description
Linna Wang
Xi’an Medical University, Xi’an, 710068, China
https://orcid.org/0000-0001-9235-1577
Sheng Zhang
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
Ji Ma
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
Jing Ni
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
Juyan Wang
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
Xiaohong Li
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
Zhilong Mu
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
Wei Han
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China,
Gaitao He
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
Lei Ma
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
Jenifei Shah
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Jay Shah
Patan Hospital, Patan Academy of Health Sciences, Kathmandu, Nepal
https://orcid.org/0000-0003-4781-7096
Fuyong Jiao
Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
Keywords
children, COVID-19, Kawasaki disease