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Kawasaki Disease- Management Strategies Given Symptoms Overlap to COVID-19: A Review

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creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorWang, Linna
dc.contributor.authorZhang, Sheng
dc.contributor.authorMa, Ji
dc.contributor.authorNi, Jing
dc.contributor.authorWang, Juyan
dc.contributor.authorLi, Xiaohong
dc.contributor.authorMu, Zhilong
dc.contributor.authorHan, Wei
dc.contributor.authorHe, Gaitao
dc.contributor.authorMa, Lei
dc.contributor.authorShah, Jenifei
dc.contributor.authorShah, Jay
dc.contributor.authorJiao, Jay
dc.date.accessioned2026-03-12T08:34:28Z
dc.date.available2026-03-12T08:34:28Z
dc.date.issued2021
dc.descriptionLinna Wang Xi’an Medical University, Xi’an, 710068, China https://orcid.org/0000-0001-9235-1577 Sheng Zhang Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China Ji Ma Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China Jing Ni Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China Juyan Wang Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China Xiaohong Li Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China Zhilong Mu Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China Wei Han Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China, Gaitao He Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China Lei Ma Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China Jenifei Shah Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Jay Shah Patan Hospital, Patan Academy of Health Sciences, Kathmandu, Nepal https://orcid.org/0000-0003-4781-7096 Fuyong Jiao Children's Hospital of Shaanxi Provincial People's Hospital, 3rd Affiliated Hospital of Medical College of Xi’an Jiao Tong University, Xi’an Shanxi, 710001, China
dc.description.abstractAbstract: Kawasaki disease is an acute, self-limiting vasculitis in children. Early treatment is necessary to prevent cardiovascular complications. The acute phase of Kawasaki disease may present with hemodynamic instability. An association between viral respiratory infections and Kawasaki disease has been reported. Studies have shown that Kawasaki and Kawasaki-like disease may be associated with and have symptoms overlapping COVID-19. Children with COVID-19 may present as Kawasaki-like disease with pediatric inflammatory multisystem syndrome, or macrophage activation syndrome. Clinicians need to be aware of the early diagnosis and management of Kawasaki disease to prevent the development of coronary artery aneurysms. The symptoms overlap of multisystem inflammatory disease seen in COVID-19 adds to the difficulties in timely diagnosis and treatment. Children with Kawasaki disease require regular follow-up plans for coronary artery aneurysms. This adds to the difficulties during the changed environment of COVID-19 for control and prevention. Missed diagnosis and early treatment of Kawasaki disease with immunoglobulin and aspirin results in the development of coronary artery aneurysm in up to 25% of cases, with grave consequences. Here, we briefly review the management of typical and atypical Kawasaki disease which has symptoms overlapping with the multisystem inflammatory disease as seen in COVID-19.
dc.identifierhttps://doi.org/10.31729/jnma.5698
dc.identifier.urihttps://hdl.handle.net/20.500.14572/5085
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectchildren
dc.subjectCOVID-19
dc.subjectKawasaki disease
dc.titleKawasaki Disease- Management Strategies Given Symptoms Overlap to COVID-19: A Review
dc.typeArticle
dspace.entity.typePublication
local.article.typeReview Article
oaire.citation.endPage424
oaire.citation.startPage417
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