Adenosine Receptors as Targets for Therapeutic Interven- tion

Suvarna, B

Publication:
Adenosine Receptors as Targets for Therapeutic Interven- tion

creativeworkseries.issn	1812-2027
dc.contributor.author	Suvarna, B
dc.date.accessioned	2025-08-27T06:34:03Z
dc.date.available	2025-08-27T06:34:03Z
dc.date.issued	2013
dc.description	Suvarna B Department of Pharmacology Melaka Manipal Medical College Manipal Campus, Manipal India
dc.description.abstract	ABSTRACT Adenosine receptors are major targets of caffeine, the most commonly consumed drug in the world. There is growing evidence that they could also be promising therapeutic targets in a wide range of conditions, including cerebral and cardiac ischaemic diseases, sleep disorders, immune and inflammatory disorders and cancer. After more than three decades of medicinal chemistry research, a considerable number of selective agonists and antagonists of adenosine receptors have been discovered, and some have been clinically evaluated, although none has yet received regulatory approval. However, recent advances in the understanding of the roles of the various adenosine receptor subtypes, and in the development of selective and potent ligands, as discussed in this review, have brought the goal of therapeutic application of adenosine receptor modulators considerably closer. KEYWORDS Adenosine, asthma, ischaemia/reperfusion injury, Parkinson’s disease, refractory primary pulmonary hypertension
dc.identifier.uri	https://hdl.handle.net/20.500.14572/2114
dc.language.iso	en_US
dc.publisher	Kathmandu university
dc.title	Adenosine Receptors as Targets for Therapeutic Interven- tion
dc.type	Article
dspace.entity.type	Publication
local.article.type	Review Article
oaire.citation.endPage	101
oaire.citation.startPage	96
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