Publication:
Clinico-epidemiological Profile of Extra Hepatic Portal Vein Obstruction: A Tertiary Care Hospital Based Retrospective Study

creativeworkseries.issn1812-2027
dc.contributor.authorSharma, R
dc.contributor.authorPradhan, B
dc.contributor.authorKarki, P
dc.contributor.authorBartaula, B
dc.date.accessioned2025-11-26T06:29:59Z
dc.date.available2025-11-26T06:29:59Z
dc.date.issued2019
dc.descriptionSharma R,1 Pradhan B,1 Karki P,2 Bartaula B2 1Division of Gastroenterology and Internal Medicine 2Department of Internal Medicine BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal.
dc.description.abstractABSTRACT Background Extra hepatic portal vein obstruction (EHPVO) is a common cause of portal hypertension in the developing countries (up to 30% of all variceal bleeders) and is second to cirrhosis in the West (up to 5-10%). Our understanding of the disease is poor compared with other illnesses. Objective To undertake a retrospective study of the clinicoepidemiological profile of Extra hepatic portal vein obstruction in a tertiary care hospital in eastern Nepal. Method All consecutive adult patients whose features were consistent with the diagnosis of extra hepatic portal vein obstruction from June 2014 to June 2016 were retrospectively analyzed to explore the various clinico-epidemiological parameters. Result A total of 58 patients were enrolled in the study with a median age of 24 years (20.5- 40). Portal vein thrombosis was the most common cause of extrahepatic portal vein obstruction. Hematemesis followed by melena were the most common presenting symptoms. All patients had splenomegaly on examination. None of the patients had clinical, biochemical or radiological evidence of chronic liver disease. Conclusion The diagnosis of extra hepatic portal venous obstruction and differentiation from cirrhosis can be easily made by characteristic clinical features, normal liver function tests and doppler ultrasound. Portal vein thrombosis (PVT) is the predominant cause of extra hepatic portal vein obstruction in Nepali patients, as seen at this tertiary care hospital in Nepal. KEY WORDS Cirrhosis, Extra hepatic portal vein obstruction, Thrombosis
dc.identifier.urihttps://hdl.handle.net/20.500.14572/3263
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectCirrhosis
dc.subjectExtra hepatic portal vein obstruction
dc.subjectThrombosis
dc.titleClinico-epidemiological Profile of Extra Hepatic Portal Vein Obstruction: A Tertiary Care Hospital Based Retrospective Study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage34
oaire.citation.startPage30
relation.isJournalIssueOfPublication72dd99d7-b8e8-4029-ae15-e344cbdb688b
relation.isJournalIssueOfPublication.latestForDiscovery72dd99d7-b8e8-4029-ae15-e344cbdb688b
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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