Publication:
Sonography as an Adjunct to Digital Mammography in Patients with Dense Breasts

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creativeworkseries.issn1999-6217
dc.contributor.authorJha, Anamika
dc.contributor.authorRegmi, Pradeep Raj
dc.contributor.authorPradhan, Huney
dc.contributor.authorThakur, Minaxi
dc.contributor.authorJoshi, Birendra Raj
dc.date.accessioned2025-07-21T07:43:24Z
dc.date.available2025-07-21T07:43:24Z
dc.date.issued2024
dc.descriptionAnamika Jha Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital https://orcid.org/0000-0001-6423-7320 Pradeep Raj Regmi Department of Radiology, Tribhuvan University Teaching Hospital https://orcid.org/0000-0001-9571-9736 Huney Pradhan Department of Radiology, Tribhuvan University Teaching Hospital Minaxi Thakur Department of Gynecology and Obstetrics, KIST Medical College and Hospital, Imadol, Lalitpur Birendra Raj Joshi Department of Radiology, Patan Academy of Health Sciences, Patan, Lalitpur
dc.description.abstractBackground: Dense breasts are associated with an increased risk of cancer and also mask lesions on mammograms. In our study, we evaluated the role of sonography as an adjunct to digital mammography in patients with dense breasts. Methods: Sonography of 676 female patients with American College of Radiology category C or D mammographic density was done in this prospective cross-sectional analytical study in the Department of Radiology, Tribhuvan University Teaching Hospital. The final imaging diagnosis was classified as per the American College of Radiology Breast Imaging Reporting and Data System categories. Tissue diagnosis was obtained in patients with sonographic category 3 solid lesions larger than 3 cm, category 4 and 5 lesions. The data were tabulated and analyzed using Statistical Package for Social Service (SPSS) for Windows version 22. Results: Additional sonography confirmed all BIRADS 1 mammograms as normal or benign, 95.7 % (112) of inconclusive, and 82.8% (n=135) of BIRADS 3 ones as benign. It had higher sensitivity and negative predictive value (100%) than mammography with similar accuracy. Most patients (479, 70.9%) had diagnostic indications. There were 540 (79.9%) cases in ACR BIRADS category c. A final diagnosis of benign (316, 46.7%) was most common, followed by normal (293, 43.4%) and malignant (67, 9.9%). The majority of the malignant lesions were Invasive Ductal Carcinoma (59, 88%). Conclusions: Additional sonography confirmed mammography findings as normal, benign, or suspicious for malignancy, definitely described morphology and extent of mass, and also guided biopsy. It had higher sensitivity than mammography in dense breasts. Keywords: Breast density; mammography; ultrasonography mammary.
dc.identifierhttps://doi.org/10.33314/jnhrc.v22i04.4735
dc.identifier.urihttps://hdl.handle.net/20.500.14572/470
dc.language.isoen_US
dc.publisherNepal Health Research Council
dc.titleSonography as an Adjunct to Digital Mammography in Patients with Dense Breasts
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage677
oaire.citation.startPage670
relation.isJournalIssueOfPublication9617a019-0e53-4864-8d10-ccd24609b880
relation.isJournalIssueOfPublication.latestForDiscovery9617a019-0e53-4864-8d10-ccd24609b880
relation.isJournalOfPublication40bd2739-8b19-447c-be60-723a1bdd1dcd

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